Results 101 to 110 of about 2,054,522 (273)

Effects of heat-reinforcing acupuncture on Drp1/Mff pathway activity and mitochondrial quality in rabbits with cold-dampness rheumatoid arthritis

针刺研究
ObjectiveTo observe the efficacy of heat-reinforcing acupuncture at “Zusanli” （ST36） in rabbits with cold-dampness rheumatoid arthritis （RA） and its impact on mitochondrial quality and the dynamin-related protein 1 （Drp1）/mitochondrial fission factor ...
JING Wei-yao, XU Cong-hui, LIU Cui, LIU Li-mei², YUAN Bo², ZHANG Xing-hua³, ZHANG Feng-fan⁴, CHEN Ping⁴, DU Xiao-zheng   +8 more
doaj   +2 more sources

Protein concentration of synovial fluid in chronic rheumatoid arthritis. Estimation of protein in the synovial fluid of chronic rheumatoid arthritis by gel filtration and paper electrophoresis [PDF]

, 1968
For the purpose to reveal the characteris6cs of the synovial fluid of the chronic rheumatoid arthritis the proteins of the synovial fluid and blood serum have been analysed by employing the methods of electrophoresis, gel filtration on Sephadex G-200 ...
Seno, Takashi
core   +1 more source

Arthroscopic Anterior Cruciate Ligament Repair With Suture Augmentation Provides Good to Excellent Midterm Functional Outcomes Despite Clinically Relevant Revision Rates

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate midterm functional outcomes after anterior cruciate ligament (ACL) repair with suture augmentation and to determine whether concomitant injuries influence patient‐reported outcomes. Methods This retrospective single‐center cohort study included patients undergoing arthroscopic ACL repair with suture augmentation between January 2017
Anna Patricia Egert, Kristian Nikolaus Schneider, Georg Gosheger, Jan Christoph Theil, Jan Frederic Weller, Alexander Klug, Georg Ahlbäumer   +6 more
wiley   +1 more source

Lessons Learned from Synovial Tissue Analysis [PDF]

The Open Rheumatology Journal, 2011
Because many inflammatory arthropathies primarily involve the synovial tissue, there has been increased interest in investigations of the pathologic changes in synovial biopsy specimens during the last 2 decades (Reviewed in [1]). This development has been stimulated by technical advances such as the advent of new methods to obtain synovial tissue ...
openaire   +3 more sources

Menopausal Hormone Therapy Decreases the Odds of Developing Soft‐Tissue Disorders of the Shoulder in Perimenopausal Women

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine whether perimenopausal women receiving menopausal hormone therapy (MHT) have decreased odds of developing soft‐tissue shoulder disorders compared with women without an active MHT prescription, specifically adhesive capsulitis, bursitis, bicipital tendinitis, calcific tendinitis, atraumatic rotator cuff tear/rupture, and shoulder ...
Isha K. Shah, Aakash K. Shah, Robert J. Burkhart, Caroline A. Dannacher, Natasha N. Desai, Jacob G. Calcei, Abigail L. Campbell   +6 more
wiley   +1 more source

EBV-encoded small RNA1 and nonresolving inflammation in rheumatoid arthritis

Kaohsiung Journal of Medical Sciences, 2013
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by perpetuated inflammation in multiple joints. To date, there is no cure for RA, and the causal factor for non-resolving inflammation in RA remains unclear.
Wen-Chan Chiu, Ching-Mei Chen, Tien-Tsai Cheng, Huey-Ling You, Shan-Fu Yu, Lin-Hsiu Weng, Hsuan-Ying Huang, Chao-Cheng Huang, Chung-Jen Chen   +8 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

RA-risk synovium exhibits DNA damage coupled with impaired DNA repair in fibroblasts

RMD Open
Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive arthritis development. Persistent DNA damage in tissues is known to drive a senescent microenvironment, genomic instability and ...
Marleen van de Sande, Aoife M O’Byrne, Tineke A de Jong, Johanna F Semmelink, Przemek M Krawczyk, Ron A Hoebe, Lisa van Baarsen   +6 more
doaj   +1 more source

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source