Results 231 to 240 of about 30,224 (276)
Mechanistic insights into non-coding RNAs regulate autophagy in chondrocytes and their contribution to osteoarthritis. [PDF]
Front Med (Lausanne)Wang B, Wang Z.
europepmc +1 more source
Extracellular ATP induces the proinflammatory phenotype transition of MH7A cells by activating P2X7 receptor. [PDF]
Purinergic SignalWang C, Hao J, Liu Y, Shen H.
europepmc +1 more source
KDM6B promotes ferroptosis in rheumatoid arthritis fibroblast-like synoviocytes via the miR-128-3p/SLC7A11 axis through H3K27me3 modification. [PDF]
J Orthop Surg ResWang B, Gao S, Liu Z, Cong Y, Wu C.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Potential role of mitochondria in synoviocytes
Clinical Rheumatology, 2020Synoviocytes are located in the synovium lining layer, which is composed of macrophage-like synoviocytes (MLS) and fibroblast-like synoviocytes (FLS) with different characteristics. Mitochondria, which exist in most cells, are two membrane-covered organelles.
Xuling Luo, Xin Long, Zhiwei Chen
exaly +3 more sources
Current Opinion in Rheumatology, 2000
The evaluation of molecular pathways has revealed various novel insights into rheumatoid arthritis pathophysiology during the past year. In addition, there is an increasing tendency toward analysis not merely of a single mechanism but rather of data addressing a substantial part of the cascade of events leading to cellular activation.
U, Müller-Ladner, R E, Gay, S, Gay
openaire +2 more sources
The evaluation of molecular pathways has revealed various novel insights into rheumatoid arthritis pathophysiology during the past year. In addition, there is an increasing tendency toward analysis not merely of a single mechanism but rather of data addressing a substantial part of the cascade of events leading to cellular activation.
U, Müller-Ladner, R E, Gay, S, Gay
openaire +2 more sources
Early synovitis—Synoviocytes and mononuclear cells
Seminars in Arthritis and Rheumatism, 1994Immunohistological observations of synovial tissues obtained at the onset of rheumatoid arthritis (RA) are limited and often reflect the diagnostic confusion inherent in any study of early synovitis. However, a critical analysis of published information and the authors' experience allow certain preliminary conclusions.
N J, Zvaifler, D, Boyle, G S, Firestein
openaire +2 more sources
Wnt signaling in rheumatoid synoviocyte activation
Modern Rheumatology, 2002Abstract Rheumatoid arthritis (RA) is a joint-specific disease with complex pathogenesis. It is characterized by synovial inflammation, cartilage loss, and joint destruction. The reasons why joint damage recurs when therapy is discontinued are not clearly understood. Several lines of evidence suggest that cartilage damage is promoted by the transformed
M, Sen, D A, Carson
openaire +2 more sources
Fibroblast-like Synoviocytes – Actors in Osteoimmunology
Osteologie, 2021AbstractRheumatoid arthritis (RA) is an immune mediated inflammatory disease (IMID), characterized by chronic inflammation and irreversible bone loss. Studies have shown that fibroblast-like synoviocytes (FLS), a key cell population in the pathogenesis of RA, have an impact on balancing bone ...
Denise Beckmann +2 more
openaire +1 more source
Endothelin-1 Production by Human Synoviocytes
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1998Immunoreactive (ir)-endothelin (ET)-l concentrations in serum samples and synovial fluids from patients with rheumatoid arthritis were higher than concentrations in sera obtained from healthy volunteers. No significant difference in ir-ET-1 concentrations in synovial fluid was observed between rheumatoid arthritis patients and osteoarthritis patients.
H, Yoshida +6 more
openaire +2 more sources
Human rheumatoid synoviocytes express functional P2X7 receptors
Journal of Molecular Medicine, 2008Human type B synoviocytes are involved in joint injury during rheumatic diseases by producing inflammatory mediators such as interleukin-6 (IL-6). The increased level of purine and pirimidine nucleotides in the synovial fluid of rheumatoid arthritis (RA) patients could activate the large family of P2 receptors.
Caporali, F. +9 more
openaire +4 more sources