Results 91 to 100 of about 68,828 (276)

Histological synovitis and radiographic damage in knee osteoarthritis: insights from a comprehensive analysis of ultrasound-guided synovial biopsies in 161 patients

open access: yesRMD Open
Objective Synovial inflammation plays a crucial role in osteoarthritis (OA) by producing key cytokines that mediate synovium–cartilage interaction and drive damage progression.
Maria-Antonietta D’Agostino   +8 more
doaj   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Assessing the relationship between wrist synovitis and anxiety: a study using clinical statistics and Mendelian randomization analysis

open access: yesJournal of Orthopaedic Surgery and Research
Background Wrist synovitis often leads to persistent pain, swelling, and limited mobility, causing significant functional impairment and psychological distress, including anxiety. Although arthroscopic synovectomy can alleviate physical symptoms, whether
Xunhao Wang   +3 more
doaj   +1 more source

Arthroscopic Debridement After Total Knee Arthroplasty Is More Effective for Synovitis Than for Ankylosis

open access: yesArthroscopy, Sports Medicine, and Rehabilitation
Purpose: To investigate the effects of arthroscopy surgery on ankylosis and synovitis after total knee arthroplasty (TKA), with patient satisfaction as the main outcome measure.
Hussein Elkousy, M.D.   +5 more
doaj   +1 more source

Per‐ and Polyfluoroalkyl Substances and Hand Osteoarthritis: Data From the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, EarlyView.
Objective To explore whether biologic levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS—reflecting the overall effect and accounting for correlations among PFAS—relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban   +14 more
wiley   +1 more source

Automated assessment of joint synovitis activity from medical ultrasound and power doppler examinations using image processing and machine learning methods

open access: yesRheumatology, 2016
Objectives : Rheumatoid arthritis is the most common rheumatic disease with arthritis, and causes substantial functional disability in approximately 50% patients after 10 years.
Rafal Cupek, Adam Ziębiński
doaj   +1 more source

Clinical Images: Successfully treated mandibular osteomyelitis by tumor necrosis factor inhibitor in SAPHO syndrome

open access: yes
Arthritis &Rheumatology, EarlyView.
Seiya Oba   +5 more
wiley   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova   +9 more
wiley   +1 more source

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

open access: yesArthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller   +15 more
wiley   +1 more source

Rubella Synovitis [PDF]

open access: yesAnnals of the Rheumatic Diseases, 1963
R J, CHAMBERS, E G, BYWATERS
openaire   +2 more sources

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