Results 111 to 120 of about 248,478 (203)

Botulinum toxin: yesterday, today, tomorrow

Нервно-мышечные болезни, 2015
Botulinum toxin (BoNT) is a bacterial neurotoxin presented with seven serotypes that inhibit neurotransmitter release from nerve endings. The serotypes of BoNT are antigenically dissimilar, act via different, but interconnected mechanisms, and are not ...
A. R. Artemenko, A. L. Kurenkov
doaj   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando, Guillermo Rodríguez‐Bey, Rosendo G. Hernández, Ángela Gento‐Caro, Ángel M. Pastor, Antonio Campos‐Caro, David González‐Forero, Bernardo Moreno‐López   +7 more
wiley   +1 more source

Fifty Years of Natural Killer Cells: Milestones and Future Horizons

Scandinavian Journal of Immunology, Volume 103, Issue 2, February 2026.
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Andreas Lundqvist, Arnika K. Wagner, Benedict J. Chambers, Carin I. M. Dahlberg, Jonas Sundbäck, Angelica Cuapio, Evren Alici, Hans‐Gustaf Ljunggren   +7 more
wiley   +1 more source

Complex polarity: building multicellular tissues through apical membrane traffic [PDF]

, 2016
The formation of distinct subdomains of the cell surface is crucial for multicellular organism development. The most striking example of this is apical-basal polarization.
Adams, Allaire, Altschuler, Ang, Aranda, Assemat, Bai, Baker, Balda, Balklava, Bedzhov, Benton, Betschinger, Blankenship, Boehlke, Bryant, Bryant, Bryant, Bulgakova, Butty, Campbell, Cancino, Chen, Chiba, Colley, Denef, Devenport, Dhekne, Eaton, Elias, Feldman, Ferrari, Fletcher, Galvez-Santisteban, Gamblin, Gangar, Gao, Gao, Gassama-Diagne, Georgiou, Gillard, Goldstein, Grawe, Graybill, Hammer, Hao, Hariharan, Harris, Harris, Harris, Hehnly, Hehnly, Hung, Hurd, Hurov, Hutterer, Hyenne, Izumi, Izumi, Joberty, Johnson, Kemphues, Klebes, Klinkert, Klose, Krahn, Kroschewski, Kumar, Kumichel, Kusakabe, Langevin, Leibfried, Lerner, Li, Li, Li, Lin, Lin, Ling, Liu, Lock, Lu, Macara, Martin-Belmonte, McGill, Melendez, Menut, Michaux, Moberg, Morais-de-Sa, Morrison, Mrozowska, Muller, Musch, Nakayama, Nakayama, Nakayama, Neisch, Ozdamar, Parsons, Pellikka, Pinal, Plant, Pocha, Pocha, Richards, Robinson, Rodriguez-Boulan, Rodriguez-Fraticelli, Rodriguez-Fraticelli, Roeth, Roland, Rossi, Sahlender, Sakamori, Sato, Satoh, Schluter, Schottenfeld-Roames, Shafaq-Zadah, Sherrard, Shewan, Shivas, Sobajima, Sollier, Stepensky, Suzuki, Takahama, Taniguchi, Tepass, Tepass, Tepass, Thuenauer, Toro, Vaccari, Vaccari, Varelas, Vermeer, Vogel, Vogel, Vreede, Wang, Wang, Wang, Wedlich-Soldner, Wei, Wiegerinck, Willenborg, Winter, Xiong, Xiong, Yamanaka, Yamanaka, Zhang, Zhang, Zhou, Zihni, Zou   +157 more
core   +1 more source

Syntaxin-16, a putative Golgi t-SNARE

European Journal of Cell Biology, 1998
Members of the syntaxin family of integral membrane proteins have recently been implicated as vesicle receptors on target membranes, coresponsible for the specificity of intracellular membrane traffic. So far, only a small number of different mammalian syntaxins have been identified.
A, Simonsen, B, Bremnes, E, Rønning, R, Aasland, H, Stenmark   +4 more
openaire   +2 more sources

Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1 [PDF]

, 2006
The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components ...
Bennett, Malcolm, Dhonukshe, Pankaj, Friml, Jiri, Kleine-Vehn, Jürgen, Swarup, Ranjan   +4 more
core   +2 more sources

Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly

IUCrJ, 2014
Membrane fusion is essential for human health, playing a vital role in processes as diverse as neurotransmission and blood glucose control. Two protein families are key: (1) the Sec1p/Munc18 (SM) and (2) the soluble N-ethylmaleimide-sensitive attachment ...
Asma Rehman, Julia K. Archbold, Shu-Hong Hu, Suzanne J. Norwood, Brett M. Collins, Jennifer L. Martin   +5 more
doaj   +1 more source

The trans-Golgi SNARE syntaxin 10 is required for optimal development of Chlamydia trachomatis

Frontiers in Cellular and Infection Microbiology, 2015
Chlamydia trachomatis, an obligate intracellular pathogen, grows inside of a vacuole, termed the inclusion. Within the inclusion, the organisms differentiate from the infectious elementary body (EB) into the reticulate body (RB). The RB communicates with
Andrea L Lucas, Scot P Ouellette, Emily J Kabeiseman, Kyle H Cichos, Elizabeth Ann Rucks   +4 more
doaj   +1 more source

SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

eLife, 2014
TANGO1 binds and exports Procollagen VII from the endoplasmic reticulum (ER). In this study, we report a connection between the cytoplasmic domain of TANGO1 and SLY1, a protein that is required for membrane fusion.
Cristina Nogueira, Patrik Erlmann, Julien Villeneuve, António JM Santos, Emma Martínez-Alonso, José Ángel Martínez-Menárguez, Vivek Malhotra   +6 more
doaj   +1 more source

Synaptic elements for GABAergic feed-forward signaling between HII horizontal cells and blue cone bipolar cells are enriched beneath primate S-cones.

PLoS ONE, 2014
The functional roles and synaptic features of horizontal cells in the mammalian retina are still controversial. Evidence exists for feedback signaling from horizontal cells to cones and feed-forward signaling from horizontal cells to bipolar cells, but ...
Christian Puller, Silke Haverkamp, Maureen Neitz, Jay Neitz   +3 more
doaj   +1 more source