Results 11 to 20 of about 248,478 (203)

Differential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8*[S] [PDF]

Journal of Lipid Research, 2009
Palmitoylation is a posttranslational modification that regulates protein trafficking and stability. In this study we investigated whether the endosomal soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) proteins syntaxin 7 ...
Yuhong He, Maurine E. Linder
doaj   +3 more sources

Open syntaxin docks synaptic vesicles.

PLoS Biology, 2007
Synaptic vesicles dock to the plasma membrane at synapses to facilitate rapid exocytosis. Docking was originally proposed to require the soluble N-ethylmaleimide-sensitive fusion attachment protein receptor (SNARE) proteins; however, perturbation studies
Marc Hammarlund, Mark T Palfreyman, Shigeki Watanabe, Shawn Olsen, Erik M Jorgensen   +4 more
doaj   +4 more sources

Docking of secretory vesicles is syntaxin dependent.

PLoS ONE, 2006
Secretory vesicles dock at the plasma membrane before they undergo fusion. Molecular docking mechanisms are poorly defined but believed to be independent of SNARE proteins.
Heidi de Wit, L Niels Cornelisse, Ruud F G Toonen, Matthijs Verhage   +3 more
doaj   +4 more sources

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions. [PDF]

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Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Jiang S, Fu J, Li S, Li Z, Zhao Q, Yin Y, Yang M, Wang Y.   +7 more
europepmc   +2 more sources

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion [PDF]

Blood, 2012
AbstractThe platelet release reaction plays a critical role in thrombosis and contributes to the events that follow hemostasis. Previous studies have shown that platelet secretion is mediated by Soluble NSF Attachment Protein Receptor (SNARE) proteins from granule and plasma membranes.
Shaojing, Ye, Zubair A, Karim, Rania, Al Hawas, Jeffery E, Pessin, Alexandra H, Filipovich, Sidney W, Whiteheart   +5 more
openaire   +4 more sources

Syntaxin 17 [PDF]

Autophagy, 2013
The phagophore (also called isolation membrane) elongates and encloses a portion of cytoplasm, resulting in formation of the autophagosome. After completion of autophagosome formation, the outer autophagosomal membrane becomes ready to fuse with the lysosome for degradation of enclosed cytoplasmic materials. However, the molecular mechanism for how the
Eisuke, Itakura, Noboru, Mizushima
openaire   +2 more sources

Syntaxin 12, a Member of the Syntaxin Family Localized to the Endosome [PDF]

Journal of Biological Chemistry, 1998
We have cloned a new member of the syntaxin family of proteins. The open reading frame encodes a polypeptide of 272 amino acids with potential coiled-coil domains and a C-terminal hydrophobic tail. Northern blot analysis showed that the transcript is fairly ubiquitous.
B L, Tang, A E, Tan, L K, Lim, S S, Lee, D Y, Low, W, Hong   +5 more
openaire   +2 more sources

Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]

, 2007
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed, Falguières, Thomas, Fradagrada, Alexandre, Johannes, Ludger, Lamaze, Christophe, Lord, Mike, Roberts, L. M. (Lynne M.), Smith, Daniel C.   +7 more
core   +1 more source

Toxoplasma gondii Syntaxin 6 is required for vesicular transport between endosomal-like compartments and the Golgi Complex [PDF]

, 2013
Apicomplexans are obligate intracellular parasites that invade the host cell in an active process that relies on unique secretory organelles (micronemes, rhoptries and dense granules) localized at the apical tip of these highly polarized eukaryotes ...
Clucas, Caroline, Ferguson, David J., Jackson, Allison J., Mamczur, Nicola J., Meissner, Markus   +4 more
core   +1 more source

Syntaxin 7, a Novel Syntaxin Member Associated with the Early Endosomal Compartment [PDF]

Journal of Biological Chemistry, 1998
Members of the syntaxin family are key molecules involved in diverse vesicle docking/fusion events. We report here the molecular, biochemical, and cell biological characterizations of a novel member (syntaxin 7) of the syntaxin family. Syntaxin 7 is structurally related to all known syntaxins.
S H, Wong, Y, Xu, T, Zhang, W, Hong
openaire   +2 more sources