Results 1 to 10 of about 7,229,609 (313)

High-Resolution Image Synthesis with Latent Diffusion Models [PDF]

open access: yesComputer Vision and Pattern Recognition, 2021
By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a guiding mechanism
Robin Rombach   +4 more
semanticscholar   +1 more source

Dynamic 3D Gaussians: Tracking by Persistent Dynamic View Synthesis [PDF]

open access: yesInternational Conference on 3D Vision, 2023
We present a method that simultaneously addresses the tasks of dynamic scene novel-view synthesis and six degree-of-freedom (6-DOF) tracking of all dense scene elements.
Jonathon Luiten   +3 more
semanticscholar   +1 more source

Taming Transformers for High-Resolution Image Synthesis [PDF]

open access: yesComputer Vision and Pattern Recognition, 2020
Designed to learn long-range interactions on sequential data, transformers continue to show state-of-the-art results on a wide variety of tasks. In contrast to CNNs, they contain no inductive bias that prioritizes local interactions.
Patrick Esser, Robin Rombach, B. Ommer
semanticscholar   +1 more source

Total wash elimination for solid phase peptide synthesis

open access: yesNature Communications, 2023
We present a process for solid phase peptide synthesis (SPPS) that completely eliminates all solvent intensive washing steps during each amino acid addition cycle.
Jonathan M. Collins   +6 more
doaj   +1 more source

Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

open access: yesMolecular Autism, 2023
Deletion of exon 2 of the trimethyllysine hydroxylase epsilon (TMLHE) gene was identified in probands with autism spectrum disorder (ASD). TMLHE encodes the first enzyme in carnitine biosynthesis, N6-trimethyllysine dioxygenase (TMLD).
Edgars Liepinsh   +6 more
doaj   +1 more source

Semantic Image Synthesis With Spatially-Adaptive Normalization [PDF]

open access: yesComputer Vision and Pattern Recognition, 2019
We propose spatially-adaptive normalization, a simple but effective layer for synthesizing photorealistic images given an input semantic layout. Previous methods directly feed the semantic layout as input to the network, forcing the network to memorize ...
Taesung Park   +3 more
semanticscholar   +1 more source

Network meta-analysis of eribulin versus other chemotherapies used as second- or later-line treatment in locally advanced or metastatic breast cancer

open access: yesBMC Cancer, 2021
Background Eribulin mesylate (ERI; Halaven®) is a microtubule inhibitor approved in the United States for metastatic breast cancer patients with at least two prior chemotherapy regimens for metastatic breast cancer, and in the European Union in locally ...
Qi Zhao   +7 more
doaj   +1 more source

Structured expert elicitation to inform long-term survival extrapolations using alternative parametric distributions: a case study of CAR T therapy for relapsed/ refractory multiple myeloma

open access: yesBMC Medical Research Methodology, 2022
Background Our aim was to extend traditional parametric models used to extrapolate survival in cost-effectiveness analyses (CEAs) by integrating individual-level patient data (IPD) from a clinical trial with estimates from experts regarding long-term ...
Dieter Ayers   +5 more
doaj   +1 more source

Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure

open access: yesFrontiers in Cell and Developmental Biology, 2021
Aim: Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite synthesized in host organisms from specific food constituents, such as choline, carnitine and betaine. During the last decade, elevated TMAO levels have been proposed as biomarkers
Melita Videja   +9 more
doaj   +1 more source

Fused isoselenazolium salts suppress breast cancer cell growth by dramatic increase in pyruvate-dependent mitochondrial ROS production

open access: yesScientific Reports, 2020
The development of targeted drugs for the treatment of cancer remains an unmet medical need. This study was designed to investigate the mechanism underlying breast cancer cell growth suppression caused by fused isoselenazolium salts.
Marina Makrecka-Kuka   +5 more
doaj   +1 more source

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