Results 121 to 130 of about 5,131,645 (316)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

2024 Evidence Synthesis Institute Conference Abstracts

open access: yes
The 2024 ESI Conference Planning Committee included the following people: Megan Kocher from University of Minnesota (PI), Amy Riegelman from University of Minnesota (Co-PI), Sarah Young from Carnegie Mellon University, Scott Marsalis from University of ...
Evidence Synthesis Institute
core  

Pesticide synthesis handbook /

open access: yes, 1996
The objective of this Handbook is to describe the basic synthesis route(s) for the manufacture of 687 pesticides. Important additional information includes the five appendices: I.
Unger, Thomas A.
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Gulf Basin Depositional Synthesis (GBDS) Phase I Project Atlas

open access: yes, 2018
The Gulf of Mexico Basin Depositional Synthesis (GBDS) is a comprehensive program of interpretation and description of the Cenozoic depositional history of the Gulf of Mexico basin that integrates well data from the onshore, shelf and upper slope areas ...
Galloway, William E.   +3 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Synthesis of Allenylphosphonates through Cu(I)-Catalyzed Coupling of Terminal Alkynes with Diazophosphonates

open access: yes, 2016
Through the Cu(I)-catalyzed coupling of diazophosphonates with terminal alkynes, an efficient method for the synthesis of allenylphosphonates has been developed.
Wua, Chenggui   +6 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Machine learning for function synthesis [PDF]

open access: yes
Function synthesis is the process of automatically constructing functions that satisfy a given specification. The space of functions as well as the format of the specifications vary greatly with each area of application.
Parsert, Julian
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Home - About - Disclaimer - Privacy