Results 101 to 110 of about 5,589,181 (255)
Unsupervised intralingual and cross-lingual speaker adaptation for HMM-based speech synthesis using two-pass decision tree construction [PDF]
, 2010 Hidden Markov model (HMM)-based speech synthesis systems possess several advantages over concatenative synthesis systems. One such advantage is the relative ease with which HMM-based systems are adapted to speakers not present in the training dataset ...
Byrne, William, Gibson, Matthew
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Mage - Reactive articulatory feature control of HMM-based parametric speech synthesis [PDF]
, 2013 In this paper, we present the integration of articulatory control into MAGE, a framework for realtime and interactive (reactive) parametric speech synthesis using hidden Markov models (HMMs). MAGE is based on the speech synthesis engine from HTS and uses
Astrinaki, Maria +6 more
core +1 more source
Parallelizing quantum circuit synthesis
, 2016 Quantum circuit synthesis is the process in which an arbitrary unitary operation is decomposed into a sequence of gates from a universal set, typically one which a quantum computer can implement both efficiently and fault-tolerantly.
Di Matteo, Olivia, Mosca, Michele
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Advanced Datapath Synthesis using Graph Isomorphism
, 2017 This paper presents an advanced DAG-based algorithm for datapath synthesis that targets area minimization using logic-level resource sharing. The problem of identifying common specification logic is formulated using unweighted graph isomorphism problem ...
Choudhury, Mihir +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Direct Observations of Twin Formation Dynamics in Binary Semiconductors
ACS Nanoscience Au, 2021 Marcus Tornberg +6 more
doaj +1 more source