Results 201 to 210 of about 7,229,609 (313)

Synthesis of thiopyran derivatives <i>via</i> [4 + 2] cycloaddition reactions. [PDF]

RSC Adv
Mousavi-Ebadia M, Safaei-Ghomi J, Nejad MJ.   +2 more
europepmc   +1 more source

Application of a Theory of Enzyme Specificity to Protein Synthesis

, 1958
Daniel E. Koshland
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Corey-Fuchs reaction enabled synthesis of natural products: a review. [PDF]

RSC Adv
Ashraf R, Zahoor AF, Khan SG, Saif MJ, Hussain SM, Raza Naqvi SA, Parveen B, Ali KG, Mansha A, Irfan A.   +9 more
europepmc   +1 more source

ENZYMATIC SYNTHESIS OF THE COENZYME A DERIVATIVES OF LONG CHAIN FATTY ACIDS

, 1953
Arthur Kornberg, W.E. Pricer
openalex   +1 more source

DIRECT EVIDENCE FOR NUCLEAR SYNTHESIS OF CYTOPLASMIC RIBOSE NUCLEIC ACID [PDF]

, 1955
Lester Goldstein, W. Plaut
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Generate what you can make: achieving in-house synthesizability with readily available resources in de novo drug design. [PDF]

J Cheminform
Hassen AK, Šícho M, van Aalst YJ, Huizenga MCW, Reynolds DNR, Luukkonen S, Bernatavicius A, Clevert DA, Janssen APA, van Westen GJP, Preuss M.   +10 more
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Application of Hosomi-Sakurai allylation reaction in total synthesis of biologically active natural products. [PDF]

Front Chem
Akwensi J, Kumah RT, Osei-Safo D, Amewu RK.   +3 more
europepmc   +1 more source