Results 221 to 230 of about 5,131,645 (316)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Synthesis and Cytotoxicity of Silicon and Germanium Containing Pyridine Oxime O-Ethers

Bioinorganic Chemistry and Applications, 2003
Edgars Abele, Ramona Abele, Pavel Arsenyan, Irina Shestakova, Iveta Kanepe, Inga Antonenko, Juris Popelis, Edmunds Lukevics   +7 more
doaj   +1 more source

Ceria support enhances activity of CoNi catalysts for ammonia synthesis under magnetic heating. [PDF]

RSC Adv
Križaj Kosi N, Sedminek A, Teržan J, Likozar B, Dolanc G, Peternel J, Makovec D, Gyergyek S.   +7 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

To seed or not to seed? That is the question for zeolite AFI crystallization. [PDF]

Chem Sci
Turizo-Pinilla EE, Martinez E, Chu-Jon C, Sundararaman S, Sankaranarayanan SKRS, Molinero V, Rimer JD.   +6 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Enantioselective Synthesis of cis-Hydroisoquinolines via Cross-[4 + 2] Cycloadditions of 2‑Pyrones and Dihydropyridines

JACS Au
Jun-Xiong He, Qi-Tao Lu, Kui Tan, Yun-Yan Tian, Yu-Qiu Cai, Nikola Topolovčan, Quan Cai   +6 more
doaj   +1 more source

Continuous-Flow Synthesis of Antiepileptic Drugs: Process Intensification, Sustainability Metrics, and Scalable Manufacturing. [PDF]

ACS Omega
Upadhyay A, Raj Pandey A, Mishra A, Tewari S.   +3 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source