Results 241 to 250 of about 5,131,645 (316)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Pyrimidine-based NNRTIs in HIV therapy: advances in synthesis, potency and structure-activity relationships. [PDF]

RSC Adv
Ali H, Hashmi MA, Ajmal N, Goraija MS, Rasool N, Siddiqua UH, Malik A.   +6 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Research Advances in Nanodrugs Targeting Lipid Metabolism Reprogramming for Colorectal Cancer Therapy. [PDF]

Int J Nanomedicine
Tang J, Liu M, Zhang R, Li Q, Wang S, Wang Y.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Amine-functionalized biochar as a green and recyclable nanocatalyst for the efficient synthesis of 1,8-naphthyridine and 2-amino-4<i>H</i>-chromene derivatives. [PDF]

RSC Adv
Hazbavi R, Hajjami M, Zolfigol MA, Siahpour Z.   +3 more
europepmc   +1 more source

Digital infrastructure to support and share daily high-throughput experimental materials research.

Faraday Discuss
Mittmann LA, Nässtrom H, Bertin E, Kapoor S, Diogo I, Itzhak A, Dalmonte G, Danielsen RT, Skytte ME, von Wenckstern H, Crovetto A, Márquez JA.   +11 more
europepmc   +1 more source

Retraction: Synthesis and characterization of an Fe-MOF@Fe₃O₄ nanocatalyst and its application as an organic nanocatalyst for one-pot synthesis of dihydropyrano[2,3-c]chromenes. [PDF]

Front Chem
Frontiers Editorial Office.
europepmc   +1 more source

Two-Dimensional MXenes for a Sustainable Future. [PDF]

J Am Chem Soc
Portugal GR, Gogotsi Y, Rosen J.
europepmc   +1 more source

The Synergy of Macrocycles and Heterocycles: A Review of Coordination Behavior, Sensing, and Functional Materials Based on Calixarenes. [PDF]

Molecules
Kalinin V, Padnya P, Stoikov I.
europepmc   +1 more source