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Synthesis of sulfonopeptides

Journal of Peptide Science, 2021
Sulfonopeptides as the sulfur analogues of natural peptides have been widely used as enzyme inhibitors due to their tetrahedral sulfonamide moiety, which can mimic the transition‐state analogues of hydrolysis of the ester and amide bonds. Synthetic methods of sulfonopeptides are reviewed.
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Synthesis of Fondaparinux: modular synthesis investigation for heparin synthesis

Carbohydrate Research, 2013
The anti-thromboembolic pentasaccharide Fondaparinux was synthesized in 36 steps for the longest linear route, with 0.017% overall yield from D-glucose. Only three kinds of protecting groups were used for hydroxyl protection, Bn, Ac, and Bz, to accomplish this complex synthesis without decreasing the synthetic efficiency.
Feng, Lin, Gaoyan, Lian, Ying, Zhou
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Reducing Adapter Synthesis to Controller Synthesis

IEEE Transactions on Services Computing, 2012
Service-oriented computing aims to create complex systems by composing less-complex systems, called services. Since services can be developed independently, the integration of services requires an adaptation mechanism for bridging any incompatibilities. Behavioral adapters aim to adjust the communication between some services to be composed in order to
Gierds, C., Mooij, A.J., Wolf, K.
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Starch: Synthesis

2004
Starch is a major component of cereal grains and forms an important part of our daily diet. A number of enzymes involved in starch biosynthesis have now been characterized. These include ADPG pyrophosphorylases, starch synthases, starch branching enzymes, and starch debranching enzymes.
Regina, A.   +3 more
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Synthesis of Platensimycin

Angewandte Chemie International Edition, 2008
AbstractIn modern drug discovery, antibodies or libraries of simple synthetic organic compounds, mostly of heterocyclic origin, are favored. Natural products play an increasingly inferior role as they are considered structurally too complex, limited in quantity, and difficult to synthesize, manipulate, and derivatize.
Tiefenbacher, Konrad, Mulzer, Johann
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Synthesis of Pyragonicin.

ChemInform, 2005
[structure: see text] A stereocontrolled convergent synthesis of the annonaceous acetogenin pyragonicin (1) is presented. The key intermediates were accessed using asymmetric Horner-Wadsworth-Emmons (HWE) methodology. A reagent controlled zinc-mediated stereoselective coupling, joining the two highly functionalized intermediates 3 and 4, then provided ...
Daniel, Strand, Tobias, Rein
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Synthesis of Bistramide A.

ChemInform, 2004
We have developed an efficient and highly stereocontrolled synthesis of bistramide A, a selective activator of protein kinase C isotype delta. Our synthetic strategy featured a novel bidirectional approach for spiroketal construction based on the ring-opening/cross-metathesis sequence employing a highly strained cyclopropenone acetal.
Alexander V, Statsuk   +2 more
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Synthesis for testability by synthesis controlling

Microprocessing and Microprogramming, 1993
Abstract The Synthesis for Testability system Synthesis Controller SC is described in this paper. SC integrates Design for Testability in usual High-Level Synthesis systems during the design process by controlling the synthesis phases. Symbolic assignments containing elements of a data flow graph are computed by the SC.
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Synthesis of Pterocellin A

Organic Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Meaghan M, O'Malley   +2 more
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A Synthesis of (+)-Saxitoxin

Journal of the American Chemical Society, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
James J, Fleming, J, Du Bois
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