Results 271 to 280 of about 12,680,478 (333)

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Flavour chemistry and metabolic engineering of microbial synthetic pyrazines: decoding the path to green manufacturing of food aroma components. [PDF]

Curr Res Food Sci
Tong W, Wang Y, Yang Y, Zou Y, Luo H, Pu J.   +5 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Influence of coprecipitation synthesis parameters on the physicochemical properties and biological effects of iron oxide nanoparticles. [PDF]

Nanoscale Adv
Reindl M, Zach V, Cvirn G, Schwaminger SP.   +3 more
europepmc   +1 more source

Synthesis of 3-Acetyl-5- benzoyl-ethyl-2-desoxy-D-riboside

, 1955
横山 金一, 藤原 一吉, 佐藤 徹雄   +2 more
openalex   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

One-pot ultrasound synthesis of polyaniline-ZnO and its synergistic effect on microbial activity. [PDF]

RSC Adv
Handore KN, Sharma SB, Chabukswar VV.
europepmc   +1 more source

Studies on Terramycin and Related Compounds. IX. Synthesis of 3-(o-Carboxy-phenyl) butyric Acid via the Reformatsky Reaction.

, 1957
Zen-ichi Horii, Ichiya Ninomiya, Yasumitsu Tamura   +2 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Genetic Risk Variants for Multiple Sclerosis and Other Loci Linked to Intrathecal Immunoglobulin G Synthesis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Pukaj A, Harroud A, Shchetynsky K, Wirsching L, Peters L, Andlauer TFM, Pääkkönen K, Bos SD, Moylett S, Dubois B, Llufriu S, Luessi F, Tackenberg B, Kowarik MC, Then Bergh F, Trebst C, Tumani H, Wildemann B, Bayas A, Havla J, Kümpfel T, Knop M, Genetics Center R, Stridh P, Hillert JA, Olsson T, Alfredsson L, Cotsapas C, Flinstad Harbo H, Zipp F, Saarela J, Baranzini SE, Berthele A, Kockum I, Hemmer B, Gasperi C, MultipleMS consortium.   +36 more
europepmc   +1 more source