Results 21 to 30 of about 12,982,812 (373)

Bio-inspired synthesis of xishacorenes A, B, and C, and a new congener from fuscol

open access: yesChemical Science, 2019
In this manuscript, we describe the conversion of fuscol, a natural product isolated in 1978, to xishacorenes A, B, and C, isolated in 2017, as well as a previously unreported congener, which we have named xishacorene D.
Alexander R Rovira   +4 more
semanticscholar   +1 more source

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors

open access: yesMolecules, 2023
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap.
Olga Bobileva   +9 more
doaj   +1 more source

Bispyrenylalkane Chemosensor for the Naked-eye Detection of Nitro-explosives

open access: yesChimica Techno Acta, 2021
Pyrene-based compounds have a great potential as fluorescent chemosensors for various analytes including common nitro-explosives, such as 2,4,6-trinitrotoluene (TNT).
I. S. Kovalev   +8 more
doaj   +1 more source

Reconstitution of recombination-associated DNA synthesis with human proteins. [PDF]

open access: yes, 2013
The repair of DNA breaks by homologous recombination is a high-fidelity process, necessary for the maintenance of genome integrity. Thus, DNA synthesis associated with recombinational repair must be largely error-free.
Grossi, Sara M   +4 more
core   +1 more source

Human-Centric Program Synthesis [PDF]

open access: yes, 2019
Program synthesis techniques offer significant new capabilities in searching for programs that satisfy high-level specifications. While synthesis has been thoroughly explored for input/output pair specifications (programming-by-example), this paper asks:
Crichton, Will
core   +2 more sources

Tacotron: Towards End-to-End Speech Synthesis [PDF]

open access: yesInterspeech, 2017
A text-to-speech synthesis system typically consists of multiple stages, such as a text analysis frontend, an acoustic model and an audio synthesis module. Building these components often requires extensive domain expertise and may contain brittle design
Yuxuan Wang   +13 more
semanticscholar   +1 more source

Ratcheting synthesis

open access: yesNature Reviews Chemistry, 2023
Synthetic chemistry has traditionally relied on reactions between reactants of high chemical potential and transformations that proceed energetically downhill to either a global or local minimum (thermodynamic or kinetic control). Catalysts can be used to manipulate kinetic control, lowering activation energies to influence reaction outcomes.
Stefan Borsley   +3 more
openaire   +3 more sources

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

open access: yes, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S.   +5 more
core   +1 more source

On the use of observation equivalence in synthesis abstraction [PDF]

open access: yes, 2011
In a previous paper we introduced the notion of synthesis abstraction, which allows efficient compositional synthesis of maximally permissive supervisors for large-scale systems of composed finite-state automata.
Fabian, Martin   +3 more
core   +2 more sources

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