B(iii)-catalyzed synthesis of spirooxindole and dihydro-2-oxopyrrole under solventless conditions in a ball mill, along with DFT computations. [PDF]
Mallah D+3 more
europepmc +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
C-2 functionalization of indoles with xanthate-lactam derivatives by radical-oxidative coupling, an approach to <i>Aspidosperma</i> alkaloids. [PDF]
Pastrana M, Miranda LD.
europepmc +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
A novel nanocatalyst praseodymium oxide (Pr<sub>6</sub>O<sub>11</sub>) for the efficient and sustainable synthesis of chromene derivatives <i>via</i> ultrasound irradiation in an aqueous hydrotropic medium. [PDF]
Patil S+6 more
europepmc +1 more source
Design and preparation of a new Ni/Arg@zeolite-Y nano-composite: investigation of its performance as a multi-functional and bio-organic catalyst for the one-pot synthesis of thieno[2,3-<i>d</i>]pyrimidinones. [PDF]
Kalhor M, Modares Z, Azizkhani V.
europepmc +1 more source
In Situ Study of Axial GaSb/GaAs Nanowire Heterostructure Formation
Mikelis Marnauza+4 more
doaj +1 more source