Results 51 to 60 of about 5,328,469 (261)

Advances in biosynthesis of chiral amide herbicides and the key enzymes: dimethenamid-P and S-metolachlor as case studies

Bioresources and Bioprocessing
Chiral amide herbicides represent a significant class of agrochemicals, widely used for effective weed control. Prominent examples include S-metolachlor and dimethenamid-P, both of which share the intermediate (S)-1-methoxy-2-propylamine, a key ...
Feng Cheng, Yi-Ling Zhou, Dan-Chen Yang, Ding-Yi Zhao, Ya-Ping Xue, Yu-Guo Zheng   +5 more
doaj   +1 more source

Predicting antibacterial activity of some Curcumin compounds: Fingerprint-based 2D-QSAR models

Scientific African
The strong spreads of bacterial infections, caused inter alia by the strong bacterial resistance to drugs, have impelled scientists to look for new antimicrobial agents.
Hajar Tebbaai, Naoual El Hamdani, Said Byadi, Aziz Aboulmouhajir   +3 more
doaj   +1 more source

Robustness of HMM-based speech synthesis [PDF]

, 2008
As speech synthesis techniques become more advanced, we are able to consider building high-quality voices from data collected outside the usual highly-controlled recording studio environment.
Ling, Z., King, S.; id_orcid, Yamagishi, Junichi, Yamagishi, J., Ling, Zhenhua, King, Simon   +5 more
core  

Gulf Basin Depositional Synthesis (GBDS) Phase I Project Atlas [PDF]

, 2018
The Gulf of Mexico Basin Depositional Synthesis (GBDS) is a comprehensive program of interpretation and description of the Cenozoic depositional history of the Gulf of Mexico basin that integrates well data from the onshore, shelf and upper slope areas ...
Galloway, William E., Buffler, Richard T., Li, X., Ganey-Curry, Patricia E.   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Molecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev   +9 more
doaj   +1 more source

Research at UIowa: A Comic Series

"Research at UIowa: A Comic Series" is a showcase of student research at the University of Iowa described in eight comics. These comics were organized by the University of Iowa student organization Connecting Science to Society and funded by the National
Rajaram, Shri Vishalini
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Stereoselective cyano translocation reaction enabled by photoenzymatic catalysis

Nature Communications
Functional-group translocation constitutes a powerful strategy in organic synthesis, allowing precise modification of molecular architectures and functional group positions.
Xinyu Duan, Jie Xu, Rulin Bai, Chenlu Jin, Yuchen Chu, Guojing Wu, Liangliang Pan, Chunlei Yang, Zhiguo Wang, Jian Xu   +9 more
doaj   +1 more source