Results 71 to 80 of about 5,131,645 (316)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

On-Surface Synthesis II

open access: yes, 2018
On-surface synthesis is appearing as an extremely promising strategy to create organic nanoarchitectures with atomic precision. Molecular building blocks holding adequate functional groups are dosed onto surfaces that support or even drive their covalent

core   +2 more sources

Palladium-Catalyzed Coupling Reaction of alpha-Diazocarbonyl Compounds with Aromatic Boronic Acids or Halides

open access: yes, 2010
Efficient palladium-catalyzed cross-coupling reactions of alpha-diazocarbonyl compounds and arylboronic acids or aryl halides have been developed. The reaction proceeds smoothly for a range of diazo compounds, boronic acids, and halides.
Cheng Peng   +11 more
core   +1 more source

Continuous‐Flow Multistep Synthesis of Active Pharmaceutical Ingredients

open access: yes, 2022
editorial reviewedThis chapter introduces the application of continuous-flow technology in the concatenated multistep synthesis of active pharmaceutical ingredients (APIs) and related compounds.
Chen, Yuesu, Monbaliu, Jean-Christophe
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The use of amine and polyetheramine hardeners in end sealing compounds for hollow fiber membrane modules

open access: yesУчёные записки Казанского университета: Серия Естественные науки
The geometry and structure of hollow fiber membranes fabricated from polysulfone by the dry-wet phase inversion method were studied with the help of scanning electron microscopy.
N. P. Bezrukov   +7 more
doaj   +1 more source

Highly Sensitive Immunosensing of Carcinoembryonic Antigen Based on Gold Nanoparticles Dotted PB@PANI Core-Shell Nanocubes as a Signal Probe

open access: yesJournal of Analytical Methods in Chemistry, 2023
Herein, a method was developed for the sensitive monitoring of carcinoembryonic antigen (CEA) by gold nanoparticles dotted prussian blue@polyaniline core-shell nanocubes (Au NPs/PB@PANI).
Dexiang Feng   +8 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Predicting antibacterial activity of some Curcumin compounds: Fingerprint-based 2D-QSAR models

open access: yesScientific African
The strong spreads of bacterial infections, caused inter alia by the strong bacterial resistance to drugs, have impelled scientists to look for new antimicrobial agents.
Hajar Tebbaai   +3 more
doaj   +1 more source

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