Results 41 to 50 of about 16,156,613 (303)

Adaptive wireless network multi-objective optimization algorithm based on image synthesis

open access: yesEURASIP Journal on Image and Video Processing, 2018
Multi-objective optimization problems can be divided into continuous multi-objective optimization problems and discrete multi-objective optimization problems, and discrete multi-objective optimization is not universal.
Jianwei Zhang, Xueya Zhang
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Optimum Path Synthesis of a Geared Five-Bar Mechanism

open access: yesAdvances in Mechanical Engineering, 2013
Most studies on path synthesis problems are to trace simple or smooth trajectories. In this work, an optimum synthesis for several special trajectories generated by a geared five-bar mechanism is studied using the one-phase synthesis method.
Wen-Yi Lin
doaj   +1 more source

Synthesis of a mobile robot spatial stabilization system based on machine learning control by symbolic regression

open access: yesRUDN Journal of Engineering Research, 2021
The spatial stabilization system synthesis problem of the robot is considered. The historical overview of methods and approaches for solving the problem of control synthesis is given.
Askhat I. Diveev   +1 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Transforming Undecidable Synthesis Problems into Decidable Problems

open access: yesEPiC Series in Computing, 2018
Synthesis holds the promise to revolutionize the development ofcomplex systems by automating the translation from specifications toimplementations. Synthesis algorithms are based on the same level ofmathematical rigor as verification algorithms but can be applied atearlier development stages, when only parts of the design areavailable.
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Optimum shape synthesis of path generating mechanisms using wavelet descriptors

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
The discrete wavelet transform is a well-known mathematical tool for shape recognition. In this study, a wavelet descriptor with two shape signatures, i.e., centroid distance and triangular centroid area, is developed for shape synthesis for path ...
Wen-Yi LIN
doaj   +1 more source

A High-Level LTL Synthesis Format: TLSF v1.1 [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
We present the Temporal Logic Synthesis Format (TLSF), a high-level format to describe synthesis problems via Linear Temporal Logic (LTL). The format builds upon standard LTL, but additionally allows to use high-level constructs, such as sets and ...
Swen Jacobs   +2 more
doaj   +1 more source

Neuronal Constraint-Handling Technique for the Optimal Synthesis of Closed-Chain Mechanisms in Lower Limb Rehabilitation

open access: yesApplied Sciences, 2022
The optimal methods for the synthesis of mechanisms in rehabilitation usually require solving constrained optimization problems. Metaheuristic algorithms are frequently used to solve these problems with the inclusion of Constraint-Handling Techniques ...
José Saúl Muñoz-Reina   +3 more
doaj   +1 more source

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