Results 71 to 80 of about 11,010,995 (253)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Behavioral and neural evidence for the underestimated attractiveness of faces synthesized using an artificial neural network

Computers in Human Behavior: Artificial Humans
Recent advancements in artificial intelligence (AI) have not eased human anxiety about AI. If such anxiety diminishes human preference for AI-synthesized visual information, the preference should be reduced solely by the belief that the information is ...
Satoshi Nishida
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Synthesize of Calcium Carbonate Its Characterization and Experimental Design in an Ultrasonic Sound Wave Environment and in the Presence of Polyelectrolyte

Gazi Üniversitesi Fen Bilimleri Dergisi, 2017
In this study, calcium carbonate (CaCO3) was synthesized by means of ultrasonic irradiation process in the presence of the water-soluble polyelectrolyte Poly(Vinyl Sulfonic Acid) (PVS).
Semra KIRBOĞA
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Plurality and Cultural Specificity of Service Design in East and Southeast Asia

This open-access book expounds on how service design has been adopted and practiced in Asia, and how it has impacted especially the East and Southeast Asian countries.

core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Il ruolo del design nella progettazione alberghiera

, 2014
l'autore è stato invitato a stendere un contributo sul ruolo del design nell'ambito della progettazione alberghiera, evidenziando le varie declinazioni della disciplina- design strategico, design dei servizi, design della comunicazione, interior design,
SCULLICA, FRANCESCO, dipartimento di design   +1 more
core  

Adsorption of Methyl Violet 2B Dye by Silica from Glass Bottle Waste

Indonesian Journal of Chemistry
In this study, silica gel was successfully synthesized using waste from chemical reagent glass bottles. The synthesized silica gel was then tested for its effectiveness in adsorbing methyl violet 2B dye.
Yatim Lailun Ni’mah, Muhammad Zidan Chisa Faqih, Suprapto Suprapto, Nabila Eka Yuningsih, Nor Laili-Azua Jamari   +4 more
doaj   +1 more source