Results 141 to 150 of about 2,945,450 (227)

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Synthetic data distillation enables the extraction of clinical information at scale. [PDF]

open access: yesNPJ Digit Med
Woo EG   +3 more
europepmc   +1 more source

A review of artificial intelligence in brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen   +4 more
wiley   +1 more source

Evaluating the use of diagnostic CT with flattening filter free beams for palliative radiotherapy: Dosimetric impact of scanner calibration variability

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Palliative radiotherapy comprises a significant portion of the radiation treatment workload. Volumetric‐modulated arc therapy (VMAT) improves dose conformity and, in conjunction with flattening filter free (FFF) delivery, can decrease treatment times, both of which are desirable in a population with a high probability of retreatment ...
Madeleine L. Van de Kleut   +2 more
wiley   +1 more source

Synthetic Data in Healthcare and Drug Development: Definitions, Regulatory Frameworks, Issues. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
Pasculli G   +13 more
europepmc   +1 more source

Impact of bulk density assignment of bone on MRI‐based abdominal region radiotherapy planning for MR‐linac workflow

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The purpose of the present study was to evaluate the impact of bone relative electron density (rED) assignment on radiotherapy planning for the abdominal region. Methods Twenty patients who received abdominal radiotherapy using MR‐Linac and underwent magnetic resonance imaging (MRI) and computed tomography (CT) simulation were analyzed.
Kota Abe   +4 more
wiley   +1 more source

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