Results 191 to 200 of about 4,799,167 (393)

On the use of synthetic data for healthcare AI in Africa: Technical performance, governance challenges, and policy readiness. [PDF]

Digit Health
Nyamawe A, Shao D.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Toward Audit-Ready Standards for Synthetic Cohorts in Health Decision Science. [PDF]

Health Data Sci
Vijayasimha M.
europepmc   +1 more source

Synthetic heparin

Current Opinion in Pharmacology, 2012
Linhardt, Robert J, Liu, Jian
openaire   +2 more sources

Wearable materials with embedded synthetic biology sensors for biomolecule detection

Nature Biotechnology, 2021
P. Nguyen, L. Soenksen, Nina M. Donghia, Nicolaas M. Angenent-Mari, Helena de Puig, Ally Huang, Rose A. Lee, Shimyn Slomovic, Tommaso Galbersanini, Geoffrey Lansberry, Hani M. Sallum, Evan M. Zhao, J. Niemi, J. Collins   +13 more
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Synthetic Cells, Synthetic Life, and Inheritance [PDF]

, 2011
Knapland, Kristine S.
core   +1 more source

Imperfect Synthetic Controls. [PDF]

J Appl Econ (Chichester Engl)
Powell D.
europepmc   +1 more source

Synthetic polarization [PDF]

Nature Methods, 2012
openaire   +2 more sources