Results 51 to 60 of about 1,905,493 (317)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects
Frontiers in Bioengineering and Biotechnology, 2023 The repair and reconstruction of bone defects and the inhibition of local tumor recurrence are two common problems in bone surgery. The rapid development of biomedicine, clinical medicine, and material science has promoted the research and development of
Honghao Yu +5 more
doaj +1 more source
The effect of maintenance on the performance of sand-filled synthetic turf surfaces [PDF]
, 2010 The effect of infill quantity and contamination on the performance of second generation sand-filled synthetic turf sports surfaces was investigated in a laboratory study.
James, Iain T., McLeod, Andrew J.
core +1 more source
Biology & Philosophy, 2019 In this essay, I discuss Dennett’s From Bacteria to Bach and Back: The Evolution of Minds (hereafter From Bacteria) and Godfrey Smith’s Other Minds: The Octopus and The Evolution of Intelligent Life (hereafter Other Minds) from a methodological perspective.
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling
Frontiers in Microbiology, 2022 Type I interferons (IFNs) are potent inhibitors of viral replication. Here, we reformatted the natural murine and human type I interferon-α/β receptors IFNAR1 and IFNAR2 into fully synthetic biological switches.
Nele Zoellner +11 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Polypropylene Surgical Meshes in Orthopedic Surgery: A Narrative Review [PDF]
Modern MedicineRestoring the continuity of the anatomical layers and the musculoskeletal soft tissues is fundamental in the reconstructive phases of all surgical procedures.
Edoardo IPPONI +6 more
doaj +1 more source
Synthetic Biology and Synthetic Knowledge [PDF]
Biological Theory, 2013 Probably the most distinctive feature of synthetic biology is its being “synthetic” in some sense or another. For some, synthesis plays a unique role in the production of knowledge that is most distinct from that played by analysis: it is claimed to deliver knowledge that would otherwise not be attained.
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source