Results 51 to 60 of about 3,358,432 (297)

Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling

open access: yesFrontiers in Microbiology, 2022
Type I interferons (IFNs) are potent inhibitors of viral replication. Here, we reformatted the natural murine and human type I interferon-α/β receptors IFNAR1 and IFNAR2 into fully synthetic biological switches.
Nele Zoellner   +11 more
doaj   +1 more source

Developments in the tools and methodologies of synthetic biology. [PDF]

open access: yes, 2014
Synthetic biology is principally concerned with the rational design and engineering of biologically based parts, devices, or systems. However, biological systems are generally complex and unpredictable, and are therefore, intrinsically difficult to ...
Freemont, P   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Utilizing Generative Adversarial Networks for Acne Dataset Generation in Dermatology

open access: yesBioMedInformatics
Background: In recent years, computer-aided diagnosis for skin conditions has made significant strides, primarily driven by artificial intelligence (AI) solutions.
Aravinthan Sankar   +5 more
doaj   +1 more source

Synthetic retina for AER systems development [PDF]

open access: yes, 2009
Neuromorphic engineering tries to mimic biology in information processing. Address-Event Representation (AER) is a neuromorphic communication protocol for spiking neurons between different layers.
Civit Balcells, Antón   +4 more
core  

Bottom-up assembly of functional intracellular synthetic organelles by droplet-based microfluidics

open access: yes, 2020
Bottom-up synthetic biology has directed most efforts toward the construction of artificial compartmentalized systems that recreate living cell functions in their mechanical, morphological, or metabolic characteristics.
Platzman, I.   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Sugar beets combinability analyzes throghut two cycles of recurrent breeding

open access: yesPlant Varieties Studying and Protection, 2013
Yield and sugar content genetic analyzes for hybrids developed engaging pollinating lines of the first and the second inbred generations throughout two cycles of recurrent breeding has underpinned the determination of regularities for combinability ...
М. О. Корнєєва   +1 more
doaj   +1 more source

Synthetic dimensions in ultracold molecules: quantum strings and membranes

open access: yes, 2018
Synthetic dimensions alter one of the most fundamental properties in nature, the dimension of space. They allow, for example, a real three-dimensional system to act as effectively four-dimensional.
Gadway, Bryce   +2 more
core   +2 more sources

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