Results 71 to 80 of about 3,358,432 (297)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Question of ‘How Are Synthetic A Priori Judgments Possible’ in Contemporary Islamic Philosophy [PDF]
Pizhūhish/hā-yi Falsafī- KalāmīAccording to Kant, the lack of progress in metaphysics is due to the fact that philosophers tried to solve metaphysical problems without examining the limits of our reason, and the outcome of these endeavors has been a dogmatic metaphysics fraught with ...
ُSeyed Ali Taheri Khorramabadi
doaj +1 more source
SREFI: Synthesis of Realistic Example Face Images
, 2017 In this paper, we propose a novel face synthesis approach that can generate an arbitrarily large number of synthetic images of both real and synthetic identities.
Banerjee, Sandipan +4 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Synthesis of Chalcones with Anticancer Activities
Molecules, 2012 Several chalcones were synthesized and their<em> in vitro </em>cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3,
Syam Mohan +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Replicating the Synthetic LBD with German Establishment Data [PDF]
, 2013 One major criticism against the use of synthetic data has been that the efforts necessary to generate useful synthetic data are so intense that many statistical agencies cannot afford them. However, we argue in this paper that the field is still evolving
Drechsler, Jörg, Vilhuber, Lars
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Journal of Pure and Applied Microbiology, 2020 The aim of this study was to compare the antibiotic potency of Cyanthillium cinereum and Moringa oleifera (natural antibiotics) against Ampicillin and Erythromycin (synthetic antibiotics) using zone of inhibition and both the natural and synthetic ...
Tresonne Headley +3 more
doaj +1 more source