Results 61 to 70 of about 2,283,693 (305)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mathematical modelling and non-linear analysis of Synthetic Gene Regulatory Networks [PDF]

open access: yes, 2010
The emerging discipline of Synthetic biology can be defined as the engineering of biology. The usefulness of a model in Synthetic biology lies in its ability to formalise the knowledge about the biological process at hand, to identify inconsistencies ...
Marucci, Lucia
core   +1 more source

Polypropylene Surgical Meshes in Orthopedic Surgery: A Narrative Review [PDF]

open access: yesModern Medicine
Restoring the continuity of the anatomical layers and the musculoskeletal soft tissues is fundamental in the reconstructive phases of all surgical procedures.
Edoardo IPPONI   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Utilizing Generative Adversarial Networks for Acne Dataset Generation in Dermatology

open access: yesBioMedInformatics
Background: In recent years, computer-aided diagnosis for skin conditions has made significant strides, primarily driven by artificial intelligence (AI) solutions.
Aravinthan Sankar   +5 more
doaj   +1 more source

Aviptadil- class effect of a synthetic vasoactive intestinal peptide as a treatment option in COVID-19 patients with severe respiratory failure

open access: yesIndian Journal of Respiratory Care, 2022
The whole world has witnessed an unimaginable, unforgettable medical disaster in the last 1 and ½ years in form of the demise of innumerable people due to the current pandemic of SARS COV-2.
Dwaipayan Sarathi Chakraborty   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Generating a Jump Distance Based Synthetic Disk Access Pattern [PDF]

open access: yes, 2006
As part of our on-going research into improving the quality of synthetic, block-level I/O workloads, we have developed an algorithm that generates a synthetic (i.e., random) disk access pattern based on both (1) a given distribution of sectors accessed ...
Kurmas, Dr. Zachary
core  

Synthesis of nine potential synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain from a scalable key intermediate

open access: yes, 2021
Synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain are of great interest, and several synthetic methods have been developed for the synthesis of these types of metabolites in the literature, which is either lengthy or inappropriate for ...
Konradsson, Peter,   +4 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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