Results 81 to 90 of about 1,905,493 (317)

Varieties of Noise: Analogical Reasoning in Synthetic Biology [PDF]

open access: yes, 2013
The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks.
Knuuttila, Tarja, Loettgers, Andrea
core  

High resolution digital holographic synthetic aperture applied to deformation measurement and extended depth of field method [PDF]

open access: yes, 2010
This paper discusses the potential of the synthetic-aperture method in digital holography to increase the resolution, to perform high accuracy deformation measurement, and to obtain a three-dimensional topology map.
Claus, Daniel
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Can synthetic biology shed light on the origin of life? [PDF]

open access: yes, 2009
It is a most commonly accepted hypothesis that life originated from inanimate matter, somehow being a synthetic product of organic aggregates, and as such, a result of some sort of prebiotic synthetic biology.
Malaterre, Christophe
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Comparative Study of the Antibiotic Potency of Natural (Cyanthillium cinereum and Moringa oleifera) and Synthetic (Ampicillin and Erythromycin) Antibiotics

open access: yesJournal of Pure and Applied Microbiology, 2020
The aim of this study was to compare the antibiotic potency of Cyanthillium cinereum and Moringa oleifera (natural antibiotics) against Ampicillin and Erythromycin (synthetic antibiotics) using zone of inhibition and both the natural and synthetic ...
Tresonne Headley   +3 more
doaj   +1 more source

A Method for Fast, High-Precision Characterization of Synthetic Biology Devices

open access: yes, 2012
Engineering biological systems with predictable behavior is a foundational goal of synthetic biology. To accomplish this, it is important to accurately characterize the behavior of biological devices.
Weiss, Ron   +4 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Estimation of Synthetic Unit Hydrographs’ Parameter Values: The Case of Wadi Al-Badan Sub-Catchment, West Bank, Palestine [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية
Developing unit hydrographs is critical in gauged catchments. Due to the lack of local data, engineers should strive to estimate discharges based on empirical (synthetic) methods in ungauged catchments.
Ghossoun Hamedallah, Sameer Shadeed
doaj   +1 more source

A Synthetic Receptor for Nicotine from a Dynamic Combinatorial Library [PDF]

open access: yes, 2012
Designing synthetic receptors that bind biologically relevant guests in an aqueous solution remains a considerable challenge. We now report a new synthetic receptor for nicotine, selected from a dynamic combinatorial library, that binds this guest in ...
Perraud, Olivier,   +12 more
core   +1 more source

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