Results 91 to 100 of about 2,283,693 (305)

Indicatori aggregati e settoriali della politica monetaria (Sectoral and aggregate indicators of monetary policy)

open access: yesMoneta e Credito, 2014
The recent debate on the management of monetary policy in Italy has paced attention on the problems of the meaning and use of synthetic indicators of monetary conditions.
S. MICOSSI, C. CARANZA
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Synthetic Speech Discrimination using Pitch Pattern Statistics Derived from Image Analysis [PDF]

open access: yes, 2012
In this paper, we extend the work by Ogihara, et al. to discriminate between human and synthetic speech using features based on pitch patterns. As previously demonstrated, significant differences in pitch patterns between human and synthetic speech can ...
Stewart, Bryan   +2 more
core  

Synthetic philosophy [PDF]

open access: yesBiology & Philosophy, 2019
In this essay, I discuss Dennett’s From Bacteria to Bach and Back: The Evolution of Minds (hereafter From Bacteria) and Godfrey Smith’s Other Minds: The Octopus and The Evolution of Intelligent Life (hereafter Other Minds) from a methodological perspective.
openaire   +3 more sources

Austin i Quine o rozróżnieniu analityczne / syntetyczne? [PDF]

open access: yesArgument, 2014
Both John Langshaw Austin and Willard Van Orman Quine were critical of the traditional division of propositions into the two categories: analytic and synthetic. Their criticism has, however, a different character.
Jan Wawrzyniak
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Comparing the toxicity of selected plant extract anthelmintics to levamisole hydrochloride and piperazine citrate in chickens

open access: yesOnderstepoort Journal of Veterinary Research
In a controlled experiment, we compared renal-hepatal, haematological and organ histopathology responses in chickens treated with Crude extracts of Capsicum annuum L. and Carica papaya L. to those treated with synthetic anthelmintics.
John Kateregga   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Transnational Governance of Synthetic Biology: Scientific uncertainty, cross-borderness and the ‘art’ of governance. For the Royal Society Science Policy Centre (UK). [PDF]

open access: yes, 2011
Synthetic biology is a new field of research that aims to 'make biology easier to engineer'. Some claim that it could revolutionise biotechnology to deliver applications for the energy, medical and agricultural sectors. However there are concerns about
Zhang, Joy Yueyue   +6 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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