Results 101 to 110 of about 3,358,432 (297)
Curvature-dimension bounds for Lorentzian splitting theorems
We analyze Lorentzian spacetimes subject to curvature-dimension bounds using the Bakry-\'Emery-Ricci tensor. We extend the Hawking-Penrose type singularity theorem and the Lorentzian timelike splitting theorem to synthetic dimensions $N\le 1$, including ...
Woolgar, Eric, Wylie, William
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
In recent years, image detection technology has faced many challenges, such as balancing efficiency and accuracy when dealing with complex environments, multi-scale, forgery generation, and dynamic scenes.
Ningrong Lai +2 more
doaj +1 more source
Smart and Functional Probiotic Microorganisms: Emerging Roles in Health-Oriented Fermentation
The incorporation of probiotic microorganisms into fermented foods has long been recognized as a promising strategy to enhance gut health and overall well-being.
Karina Teixeira Magalhães +5 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Analytic, Paradoxical, and Synthetic Sentences on ABC and The Hard Way Song Lyrics
This research aims to identify and classify; analytic, paradoxical, and synthetic sentences which are logical types of sentences in the song lyric of ABC by The Jackson 5 and The Hard Way by The Kinks in order to get the virtue of meanings of the lyrics.
Frans Sayogie +2 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

