Results 111 to 120 of about 916,052 (349)

Synthetical Chemistry in its Relation to Biology [PDF]

, 1907

openalex   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Synthetic microbe-to-plant communication channels

Nature Communications
Plants and microbes communicate to collaborate to stop pests, scavenge nutrients, and react to environmental change. Microbiota consisting of thousands of species interact with each other and plants using a large chemical language that is interpreted by ...
Alice Boo, Tyler Toth, Qiguo Yu, Alexander Pfotenhauer, Brandon D. Fields, Scott C. Lenaghan, C. Neal Stewart, Christopher A. Voigt   +7 more
doaj   +1 more source

Synthetic peptides in biology and medicine [PDF]

, 1987
Dwayne Elmore
openalex   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Stem cell and gene therapies for leukodystrophies

Molecular Therapy: Methods & Clinical Development
Leukodystrophies form a group of rare genetic disorders characterized by the progressive degeneration of white matter in the brain, often presenting in childhood with life-threatening consequences.
Wenhao Lin, Min Zhang, Sirui Zheng, Qizhou Lian   +3 more
doaj   +1 more source

CRISPR for Bio-Art? [PDF]

, 2018
Es el resumen de mi ponencia oral (seleccionada entre todas las propuestas recibidas de todo el mundo, siendo una de las 12 únicas comunicaciones orales y la única con representante español en dicho Simposio).This communication will explain the ...
Medina, Miguel Ángel
core  

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Establishment of CRISPR‐STAR System to Realise Simultaneous Transcriptional Activation and Repression in Yarrowia lipolytica

Microbial Biotechnology
The ability to regulate gene expression in multiple directions is crucial to maximise the production of microbial cell factories. However, the lack of a regulatory tool that can simultaneously activate and repress multiple genes restricts the ...
Yaru Chen, Mengxu Li, Xuanwei Liu, Qiyang Duan, Lin Xiao, Luxin Wang, Congcong Huang, Hao Song, Yingxiu Cao   +8 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source