Results 111 to 120 of about 2,952,613 (401)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Synthetic biology-inspired development of live attenuated influenza vaccines
npj VaccinesLive attenuated influenza vaccines (LAIVs) provide robust, cross-protective immunity but have traditionally been developed empirically and are associated with safety concerns.
Qisi Zhang +14 more
doaj +1 more source
Publisher Correction: Encryption and steganography of synthetic gene circuits
Nature Communications, 2019 The original version of this Article contained an error in Fig. 4. In the lower part of the three gene circuit diagrams in panel b, the flat-headed arrow linking lambdaCI to the tetR promoter incorrectly pointed to the tetR gene body.
Oliver Purcell +3 more
doaj +1 more source
Science and Technology Studies in Policy: the UK Synthetic Biology Roadmap [PDF]
, 2019 In this paper, we reflect on our experience as Science and Technology Studies (STS) researchers who were members of the working group that produced A Synthetic Biology Roadmap for the UK in 2012.
Calvert, J., Marris, C.
core +2 more sources
Alternative Strategies for Microbial Remediation of Pollutants via Synthetic Biology
Frontiers in Microbiology, 2020 Continuous contamination of the environment with xenobiotics and related recalcitrant compounds has emerged as a serious pollution threat. Bioremediation is the key to eliminating persistent contaminants from the environment.
S. Jaiswal, Pratyoosh Shukla
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Wearable materials with embedded synthetic biology sensors for biomolecule detection
Nature Biotechnology, 2021 P. Nguyen +13 more
semanticscholar +1 more source
Vibrio natriegens: An ultrafast-growing marine bacterium as emerging synthetic biology chassis.
Environmental Microbiology, 2020 The marine bacterium Vibrio natriegens is the fastest-growing non-pathogenic bacterium known to date and is gaining more and more attention as an alternative chassis organism to Escherichia coli.
J. Hoff +5 more
semanticscholar +1 more source