Results 261 to 270 of about 435,061 (337)

A new era of synthetic biology-microbial community design. [PDF]

Synth Biol (Oxf)
Matuszyńska A, Ebenhöh O, Zurbriggen MD, Ducat DC, Axmann IM.   +4 more
europepmc   +1 more source

Association Between Metabolic Syndrome and Radiographic Changes in Psoriatic Arthritis: A Cohort Study

Arthritis Care &Research, EarlyView.
Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf, Shangyi Gao, S. Ercan Tunc, Justine Y. Ye, Daniel Pereira, Dafna D. Gladman, Vinod Chandran   +6 more
wiley   +1 more source

Modulating Microbial Materials - Engineering Bacterial Cellulose with Synthetic Biology. [PDF]

ACS Synth Biol
Malcı K, Li IS, Kisseroudis N, Ellis T.
europepmc   +1 more source

Placebo Effect Sizes in Clinical Trials of Knee Osteoarthritis Using Intra‐Articular Injections of Biologic Agents

Arthritis Care &Research, EarlyView.
Objective Patients with knee osteoarthritis rely on symptomatic treatments, in which up to 75% of the pain reduction can be attributed to the placebo effect. This effect may vary based on treatment type (eg, biologics vs nonbiologic injection) and route of administration (eg, intra‐articular vs topical vs oral).
Johanna M. Borst, Severin Ruoss, Ian Palmer, Trevor Smith, Kenneth Kalunian, Samuel R. Ward   +5 more
wiley   +1 more source

The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review

Arthritis Care &Research, Accepted Article.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co‐morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C Scott   +3 more
wiley   +1 more source

Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology. [PDF]

Front Pharmacol
Li C, Du M, Han Y, Sun W, Chen Z, Liu Q, Zhu H, Zhao L, Li S, Wang J.   +9 more
europepmc   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Computational Synthetic Biology Enabled through JAX: A Showcase. [PDF]

ACS Synth Biol
Gallup O, Sechkar K, Towers S, Steel H.
europepmc   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

Elucidating the Supramolecular Interaction of Positively Supercharged Fluorescent Protein with Anionic Phthalocyanines

Advanced Biology, EarlyView.
Positively supercharged mGreenLatern protein is self‐assembled electrostatically with negatively charged zinc phthalocyanines to yield bio‐based photoactive materials in aqueous media. The addition of phthalocyanines results in the formation of large complexes fully quenching of the protein fluorescence. The results indicate an energy transfer from the
Sharon Saarinen, Ramsha Khan, Marta Patrian, Juan Pablo Fuenzalida‐Werner, Rubén D. Costa, Petr Zimcik, Veronika Novakova, Tero‐Petri Ruoko, Nikolai V. Tkachenko, Eduardo Anaya‐Plaza, Mauri A. Kostiainen   +10 more
wiley   +1 more source