Results 101 to 110 of about 13,766,532 (237)

Progress in constructing functional coacervate systems using microfluidics

BMEMat
Coacervates formed by liquid‐liquid phase separation play significant roles in a variety of intracellular and extracellular biological processes. Recently, substantial efforts have been invested in creating protocells using coacervates.
Yuhao Geng, Jing Yu
doaj   +1 more source

Cell-specific cargo delivery using synthetic bacterial spores [PDF]

, 2020
Minsuk Kong, Taylor B. Updegrove, Maira A. Constantino, Devorah Gallardo, I-Lin Wu, David Fitzgerald, Kandice Tanner, Kumaran S. Ramamurthi   +7 more
openalex   +1 more source

Synthetic mixed-signal computation in living cells

Nature Communications, 2016
Digital and analogue gene circuits each have distinct advantages in natural and engineered cells. Here, Rubens et al. engineer synthetic gene circuits that implement mixed-signal digital and analogue computations in living cells.
Jacob R. Rubens, Gianluca Selvaggio, Timothy K. Lu   +2 more
doaj   +1 more source

VR-10 Thrombospondin-1 Synthetic Polypeptide’s Impact on Rhesus Choroid-Retinal Endothelial Cells

Cellular Physiology and Biochemistry, 2018
Background/Aims: This study aimed to investigate the effects of the VR-10 TSP-1 synthetic polypeptide on cytokines and the proliferation and migration of endothelial cells, as well as exploring a new method for anti-ocular neoangiogenesis.
Run Tian, Fang  Han, Jun Yang, Hai-Yan Zhao, Yan Mei, Ai-Ping Deng, Lin Fang, Xi-Rui Zhang   +7 more
doaj   +1 more source

Minimal Cell Motility System Reconstructed in Synthetic Bacterium Driven by Bacterial Actin MreBs

, 2023
Hana Kiyama, Shigeyuki KAKIZAWA, Makoto Miyata   +2 more
openalex   +2 more sources

FIGURE 1 from PARP Inhibitors Effectively Reduce MAPK Inhibitor Resistant Melanoma Cell Growth and Synergize with MAPK Inhibitors through a Synthetic Lethal Interaction <i>In Vitro</i> and <i>In Vivo</i>

, 2023
Lisa Marie Fröhlich, Heike Niessner, Birgit Sauer, Sofie Kämereit, Eftychia Chatziioannou, Simon Riel, Tobias Sinnberg, Birgit Schittek   +7 more
openalex   +1 more source

Glycogen engineering improves the starvation resistance of mesenchymal stem cells and their therapeutic efficacy in pulmonary fibrosis

eLife
Mesenchymal stem cells (MSCs) are widely used in regenerative medicine, including the treatment of pulmonary fibrosis. However, implanted MSCs disappear within days, constraining therapeutic efficacy, which is largely attributed to nutrient deprivation ...
Yongyue Xu, Mamatali Rahman, Zhaoyan Wang, Bo Zhang, Hanqi Xie, Lei Wang, Haowei Xu, Xiaodan Sun, Shan Cheng, Qiong Wu   +9 more
doaj   +1 more source

Building a Synthetic Cell Together

Nature Communications
Synthetic cells (SynCells) are artificial constructs designed to mimic cellular functions, offering insights into fundamental biology, as well as promising impact in the fields of medicine, biotechnology, and bioengineering. Achieving a functional SynCell from the bottom up, i.e.
S. Giaveri, Z. Abil, S. Kohyama, M. Fu, A. Levrier, K. Adamala, W. Chinantuya, C. Dekker, N. Deng, J. Fredens, K. Hagino, K. Jahnke, X. Li, A. B. Lindner, C. Liu, S. Majumder, V. Noireaux, P. Schwille, I. N. Westensee   +18 more
openaire   +3 more sources

Novel directions in molecular systems design: The case of light-transducing synthetic cells

Communicative & Integrative Biology, 2017
Important progresses have been achieved in the past years in the field of bottom-up synthetic biology, especially aiming at constructing cell-like systems based on lipid vesicles (liposomes) entrapping both biomolecules or synthetic compounds.
Pasquale Stano, Emiliano Altamura, Fabio Mavelli   +2 more
doaj   +1 more source

Author Correction: Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator [PDF]

, 2021
David T. Riglar, David Richmond, Laurent Potvin-Trottier, Andrew A Verdegaal, Alexander D. Naydich, Somenath Bakshi, Emanuele Leoncini, Lorena Lyon, Johan Paulsson, Pamela A. Silver   +9 more
openalex   +1 more source