Results 181 to 190 of about 1,906,510 (288)

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

Advanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang, Tsz Kwan Yau, Joyce Tse, Tsz Ho Li, Dongjie Hu, Yong Juan Zhao, Ting‐Fung Chan   +6 more
wiley   +1 more source

RadiolGAN: Multicenter Feasibility Study of Synthetic CT From 3D Ultra-Short Echo Time MRI for Enhanced Pulmonary Radiologic Sign Visualization. [PDF]

J Magn Reson Imaging
Zhu X, Xia W, Xie X, Li Y, Lv Y, Sun X, Zhu Y, Shang S, Zhou L, Mo X, Bao Z, Shi J, Ye J, Cui Y, Tang C, Huang W.   +15 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

AI-based synthetic CT attenuation correction enables reliable quantitative SPECT in unilateral condylar hyperplasia. [PDF]

EJNMMI Phys
Kovács AR, Juhász EF, Czina P, Budai Á, Varga J, Husztik B, Kovács Á, Szoliková M, Boda R, Kovács KS, Garai I, Barna SK.   +11 more
europepmc   +1 more source

Machine Learning‐Assisted KCl‐CaCl2‐LiCl Electrolyte Design for Low‐Temperature, High‐Performance Calcium‐Based Liquid Metal Batteries

Advanced Science, EarlyView.
A machine learning‐assisted framework optimizes the KCl‐CaCl2‐LiCl ternary electrolyte. The optimized 13:35:52 mol% composition enables Ca‐based liquid metal batteries to operate stably at 480 °C, with >99.5% coulombic efficiency, ultralow self‐discharge, and excellent cycling stability, advancing low‐temperature large‐scale energy storage.
Xinglin Zhou, Lei Huang, Yan Zhou, Xiaohui Ning   +3 more
wiley   +1 more source

Self-learning GAN based synthetic CT generation: unlocking CBCT-based adaptive radiotherapy. [PDF]

Front Oncol
Prunaretty J, Colombo L, Romdhani S, Teboul O, Azria D, Paragyios N, Fenoglietto P.   +6 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Attenuation correction of cardiac ⁸²Rb pet using deep learning generated synthetic CT. [PDF]

EJNMMI Phys
Jørgensen K, Lassen ML, Andersen FL, Hasbak P, Ladefoged CN.   +4 more
europepmc   +1 more source

CT vs. MRI-based synthetic CT: accuracy of thoracic and lumbar pedicle screw placement using 3D-printed guides

Purpose: 3D-printed patient-specific guides enable accurate pedicle screw placement in the treatment of paediatric spinal deformities. MRI-based synthetic CT (sCT) eliminates the radiation exposure associated with the preoperative planning CT, while ...
Streekstra, Geert J., DHS 3D Lab, Regenerative Medicine and Stem Cells, Orthopaedie Opleiding, Cool, Jules, Kruyt, Moyo C., MS Orthopaedie Algemeen, Schlösser, Tom P.C., van Royen, Barend J., Magré, Joëll, Lafranca, Peter P.G., Dobbe, Johannes G.G.   +11 more
core  

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source