Results 101 to 110 of about 1,035,049 (261)

Predicting the Multiphotonic Absorption in Graphene by Machine Learning

AI
This study analyzes the nonlinear optical properties exhibited by graphene, focusing on the nonlinear absorption coefficient and the nonlinear refractive index.
José Zahid García-Córdova, Jose Alberto Arano-Martinez, Cecilia Mercado-Zúñiga, Claudia Lizbeth Martínez-González, Carlos Torres-Torres   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

ChildDiffusion: Unlocking the Potential of Generative AI and Controllable Augmentations for Child Facial Data Using Stable Diffusion and Large Language Models

IEEE Access
Ensuring the availability of child facial datasets is essential for advancing AI applications, yet legal, ethical, and data scarcity concerns pose significant challenges. Current generative models such as StyleGAN excel at producing synthetic facial data
Muhammad Ali Farooq, Wang Yao, Peter Corcoran   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

JailbreakTracer: Explainable Detection of Jailbreaking Prompts in LLMs Using Synthetic Data Generation

IEEE Access
The emergence of Large Language Models (LLMs) has revolutionized natural language processing (NLP), enabling remarkable advancements across various applications.
Md. Faiyaz Abdullah Sayeedi, Maaz Bin Hossain, Md. Kamrul Hassan, Sabrina Afrin, Molla Md. Sabit Hossain, Md. Shohrab Hossain   +5 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Synthetic Data: Generate Avatar Data on Demand

Anonymization is crucial for the sharing of personal data in a privacy-aware manner yet it is a complex task that requires to set up a trade-off between the robustness of anonymization (i.e., the privacy level provided) and the quality of the analysis that can be expected from anonymized data (i.e., the resulting utility). Synthetic data has emerged as
Thomas Lebrun, Louis Béziaud, Tristan Allard, Antoine Boutet, Sébastien Gambs, Mohamed Maouche   +5 more
openaire   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source