Results 81 to 90 of about 2,406,574 (279)

Synthetic Data for Social Good

CoRR, 2017
Presented at the Data For Good Exchange ...
Bill Howe, Julia Stoyanovich, Haoyue Ping, Bernease Herman, Matt Gee   +4 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Synthetic patient and interview transcript creator: an essential tool for LLMs in mental health

Frontiers in Digital Health
Developing high-quality training data is essential for tailoring large language models (LLMs) to specialized applications like mental health. To address privacy and legal constraints associated with real patient data, we designed a synthetic patient and ...
Aleyna Warner, Aleyna Warner, Jeffrey LeDue, Jeffrey LeDue, Yutong Cao, Yutong Cao, Joseph Tham, Joseph Tham, Timothy H. Murphy, Timothy H. Murphy   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Synthetic Data for Fairness: Bias Mitigation in Facial Attribute Recognition

IEEE Open Journal of the Computer Society
Bias mitigation in soft facial attribute recognition remains a critical and underexplored challenge in the development of fair and accountable Artificial Intelligence (AI) systems.
Lucia Cascone, Marco Di Maio, Vincenzo Loia, Mattia Maucioni, Michele Nappi, Chiara Pero   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Synthetic Scientific Image Generation with VAE, GAN, and Diffusion Model Architectures

Journal of Imaging
Generative AI (genAI) has emerged as a powerful tool for synthesizing diverse and complex image data, offering new possibilities for scientific imaging applications.
Zineb Sordo, Eric Chagnon, Zixi Hu, Jeffrey J. Donatelli, Peter Andeer, Peter S. Nico, Trent Northen, Daniela Ushizima   +7 more
doaj   +1 more source

Synthetic Aperture Radar (SAR) data processing [PDF]

The available and optimal methods for generating SAR imagery for NASA applications were identified. The SAR image quality and data processing requirements associated with these applications were studied. Mathematical operations and algorithms required to
Ahr, H. A., Ausherman, D. A., Beckner, F. L., Cutrona, L. J., Francisco, S., Harrison, R. E., Heuser, J. S., Jordan, R. L., Justus, J., Manning, B.   +9 more
core   +1 more source

How Protective Are Synthetic Data? [PDF]

, 2008
This short paper provides a synthesis of the statistical disclosure limitation and computer science data privacy approaches to measuring the confidentiality protections provided by fully synthetic data. Since all elements of the data records in the release file derived from fully synthetic data are sampled from an appropriate probability distribution ...
John M. Abowd, Lars Vilhuber
openaire   +1 more source