Results 131 to 140 of about 169,227 (310)

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Novel "green" catalysts for controlled ring-opening polymerization of lactide [PDF]

, 2010
Syntéza polylaktidu (PLA) polymerací za otevření kruhu cyklického monomeru (ROP) může být uskutečněna různými způsoby. Literatura uvádí více než 100 katalytických systémů, jejichž pomocí lze polylaktid a jiné biodegradabilní alifatické polyestery získat.
Surman, František
core  

Comparison of Performance Properties of Muds Formulated With Synthesized C14 and C16 Esters of Lauric Acid

Journal of Applied Sciences and Environmental Management
Drilling muds have relied on a range of base fluids, with mineral oil-based formulations dominating the landscape for decades. However, mineral oil-based muds contain a plethora of toxic aromatic compounds which are persistent in the environment. Hence,
I. Orji, I. E. Ekpo, M. U. Ibezim-Ezeani, O. Akaranta   +3 more
doaj  

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

The Effect of Dissolved Water on the Tribological Properties of Polyalkylene Glycol and Polyolester Oils [PDF]

, 1994
The effect of water dissolved in polyalkylene glycol and polyolester oils on the tribological behavior of two material contact pairs in three test environments is evaluated.
Cusano, C., Glabbeek, W.H. Van, Sheiretov, T.K.   +2 more
core  

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Investigation of \u3cem\u3ede novo\u3c/em\u3e cholesterol synthetic capacity in the gonads of goldfish (\u3cem\u3eCarassius auratus\u3c/em\u3e) exposed to the phytosterol beta-sitosterol [PDF]

, 2006
Total and intra-mitochondrial gonadal cholesterol concentrations are decreased in fish exposed to the phytoestrogen beta-sitosterol (beta-sit). The present study examined the potential for beta-sit to disrupt de novo cholesterol synthesis in the gonads ...
Drolet, Melissa, MacLatchy, Deborah L., Sharpe, Rainie L.   +2 more
core   +1 more source

Synthesis of α‐Pentafluorosulfanylated‐β2,3‐Amino Esters

ChemistryEurope
Incorporating the SF5 group into organic molecules is a powerful strategy for pushing the boundaries of chemistry and driving progress in drug discovery.
Thi Mo Nguyen, Guilhem Colomer, Oscar Maugue‐Sauze, Nicolas Blanchard, Vincent Bizet, Dominique Cahard   +5 more
doaj   +1 more source

Comparison of Aging Effect of Ester Liquids and Mineral Oil in Semi-Uniform Field Geometry under Lightning Impulse Voltage and Standard Compliant AC Voltage Testing

Energies
This study examines and compares the breakdown and aging properties of five insulating liquids. Additionally, the influence of different voltage polarities on these properties was analyzed to investigate the effect of aging on polarity behavior under ...
Sabrina Krügel, Ronald Plath
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source