Results 101 to 110 of about 4,015,932 (307)
Mathematical modelling and non-linear analysis of Synthetic Gene Regulatory Networks [PDF]
The emerging discipline of Synthetic biology can be defined as the engineering of biology. The usefulness of a model in Synthetic biology lies in its ability to formalise the knowledge about the biological process at hand, to identify inconsistencies ...
Marucci, Lucia
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
After the persistent criticism of the gross national income (GDP) as a measure of well-being, numerous proposals for synthetic indicators of different dimensions have emerged.
Diego M. Roldán +4 more
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Varieties of Noise: Analogical Reasoning in Synthetic Biology [PDF]
The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks.
Knuuttila, Tarja, Loettgers, Andrea
core
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Studies on natural and synthetic high molecular weight forms of urokinase
Studies on natural and synthetic high molecular weight forms of ...
SCHIAVON, ODDONE +4 more
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Synthetic data for the Bedforms Analysis Toolkit for Multiscale Modeling (Bedforms-ATM)
Bedforms Analysis Toolkit for Multiscale Modeling (Bedforms-ATM) is an open source MATLAB software which is aimed to standardize the analysis of variability of bed forms.
Ronald R Gutierrez (8018675) +1 more
core +1 more source

