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Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand
Oncogene, 2021Parasvi S Patel +2 more
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Precision medicine by synthetic lethality
Science Signaling, 2015Inhibition of WEE1 selectively kills H3K26 methylation-deficient cells.
openaire +1 more source
Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines
Cell Systems, 2021Barbara De Kegel +2 more
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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
Molecular Cell, 2021Graeme Hewitt +2 more
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Synthetic lethality: A promising therapeutic strategy for hepatocellular carcinoma
Cancer Letters, 2020Xiao Xu
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Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
Cancer Cell, 2019James Degar +2 more
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Synthetic lethality on drug discovery: an update on cancer therapy
Expert Opinion on Drug Discovery, 2020Mohammad Shahar Yar +2 more
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