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Precision medicine by synthetic lethality

Science Signaling, 2015
Inhibition of WEE1 selectively kills H3K26 methylation-deficient cells.
openaire   +1 more source

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Molecular Cell, 2021
Graeme Hewitt   +2 more
exaly  

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Cancer Cell, 2019
James Degar   +2 more
exaly  

Synthetic lethality on drug discovery: an update on cancer therapy

Expert Opinion on Drug Discovery, 2020
Mohammad Shahar Yar   +2 more
exaly  

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