Results 161 to 170 of about 1,368,992 (302)

Preparation and Characterization of Escherichia coli Liposomes as a New Drug Delivery System to Colon Cancer

Biological Journal of Microorganism, 2016
Introduction: Liposomes are spherical vesicles composed of concentric phospholipid bilayers that can entrap hydrophilic, hydrophobic drugs. Liposomes can be prepared from natural phospholipids, synthetic lipids or bacterial lipids.
Mohammad Kargar, SOMAYEH handali, Eskandar Moghimipour, Zahra Ramezani   +3 more
doaj  

Synthesis of novel cationic lipids for preparation of liposomes to be used in gene therapy of glioma

, 2003
The synthesis of a series of cationic lipids for the preparation of liposomes to be used in gene therapy is described.
MOSSA G, NAPOLETANO R, BONADIES F, ESPOSITO C, BIANCO A, CAMETTI C, ORTAGGI G   +6 more
core  

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Small Extracellular Vesicle and Total Lipid Profiles Provide a Diagnostic Advantage Over CA-125 Across Ovarian Cancer Subtypes. [PDF]

J Extracell Vesicles
Rani S, Guanzon D, Lai A, Scholz-Romero K, Perrin L, Lourie R, Joshi V, McCart Reed AE, Ferguson K, Handberg A, Möller A, Salomon C.   +11 more
europepmc   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Synthesis of deuterated ALC-0315 for contrast variation SANS analysis of lipid nanoparticles. [PDF]

RSC Adv
Zhang HH, Leite W, Pingali SV, Nusser B, Urban VS, O'Neill H.   +5 more
europepmc   +1 more source

Bioactive compounds in plants: a new food perspective

, 2018
Antioxidants refer to a group of compounds that are able to delay or inhibit the oxidation of lipids or other biomolecules, and thus prevent or repair the damage of body cells caused by oxygen (Shahidi and Naczk, 2004; Tachakittirungrod et al., 2007 ...
Ricci Antonella, Lo Sterzo Claudio, Pellegrini Marika, Palmieri Sara   +3 more
core  

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research. [PDF]

FEBS Lett
Presutti C, Poolman B.
europepmc   +1 more source