Results 61 to 70 of about 884,751 (294)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
J, 2020 Media articles have claimed that “synthetic mineral oil saturated hydrocarbons (MOSH)”, which are used in many cosmetics such as lip balms, are unsafe at any dose and should be replaced with natural alternatives.
Louise Chandon
doaj +1 more source
Characteristics of human spermatozoa harvested in culture media with and without serum proteins [PDF]
, 2018 This study was aimed to determine the efficiency of synthetic protein-free media in spermatozoa washing, preparation and retention of the activity of washed spermatozoa over short periods in vitro.
Ghofraan A. Ata’Allah, +7 more
core
A Forward-Design Approach to Increase the Production of Poly-3-Hydroxybutyrate in Genetically Engineered Escherichia coli [PDF]
, 2015 Biopolymers, such as poly-3-hydroxybutyrate (P(3HB)) are produced as a carbon store in an array of organisms and exhibit characteristics which are similar to oil-derived plastics, yet have the added advantages of biodegradability and biocompatibility ...
Bower, I +12 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
İmgelemYapay zekâ (YZ) tarafından üretilen sentetik medyanın yaygınlaşması, dijital bilgi ekosistemini kökten değiştirmekte ve özellikle bu teknolojilerin en yoğun kullanıcısı olan Z kuşağı için yeni fırsatlar ve zorluklar ortaya koymaktadır.
Gıyasettin Yıldız
doaj +1 more source
Imaging point sources in heterogeneous environments
, 2019 Imaging point sources in heterogeneous environments from boundary or far-field measurements has been extensively studied in the past. In most existing results, the environment, represented by the refractive index function in the model equation, is ...
Ren, Kui, Zhong, Yimin
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
PENGARUH KONSENTRASI NaCl TERHADAP AKTIVITAS SPESIFIK PROTEASE EKSTRASELULER DARI BAKTERI HALOFILIK HASIL ISOLASI BITTERN TAMBAK GARAM MADURA [PDF]
, 2009 Protease halofil dapat dimanfaatkan pada proses fermentasi makanan seperti pada pembuatan kecap ikan. Penelitian ini bertujuan untuk memperoleh bakteri halofilik dari isolat bittern tambak garam Madura dan mengisolasi protease halofil ekstraseluler serta
Asy’ari, M. +2 more
core
Tissue multifractality and Born approximation in analysis of light scattering: a novel approach for precancers detection [PDF]
, 2014 Multifractal, a special class of complex self-affine processes, are under recent intensive investigations because of their fundamental nature and potential applications in diverse physical systems.
Ch Ivanov Plamen +20 more
core +1 more source