Results 11 to 20 of about 1,066,470 (312)

Synthetic Methods of Phosphonopeptides. [PDF]

open access: yesMolecules, 2020
Phosphonopeptides are phosphorus analogues of peptides and have been widely applied as enzyme inhibitors and antigens to induce catalytic antibodies. Phosphonopeptides generally contain one aminoalkylphosphonic acid residue and include phosphonopeptides with C-terminal aminoalkylphosphonic acids and phosphonopeptides with a phosphonamidate bond.
Xu J.
europepmc   +5 more sources

Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine. [PDF]

open access: yesMolecules, 2021
In the context of naturally occurring nitrogen heterocycles, nicotine is a chiral alkaloid present in tobacco plants, which can target and stimulate nicotinic acetylcholine receptors (nAChRs), a class of ligand-gated ion channels commonly located ...
Panda B, Albano G.
europepmc   +2 more sources

Synthetic Control Methods for Proportions

open access: yes
Synthetic control methods are extensively utilized in political science for estimating counterfactual outcomes in case studies and difference-in-differences settings, often applied to model counterfactual proportional data. However, the conventional synthetic control methods are designed for univariate outcomes, leading researchers to model ...
Konstantin Bogatyrev, Lukas Stoetzer
openaire   +2 more sources

The Inclusive Synthetic Control Method [PDF]

open access: yesSSRN Electronic Journal, 2020
We introduce the inclusive synthetic control method (iSCM), a modification of synthetic control methods that includes units in the donor pool potentially affected, directly or indirectly, by an intervention. This method is ideal for situations where including treated units in the donor pool is essential or where donor units may experience spillover ...
Di Stefano, Roberta, Mellace, Giovanni
openaire   +3 more sources

The Augmented Synthetic Control Method [PDF]

open access: yesJournal of the American Statistical Association, 2021
The synthetic control method (SCM) is a popular approach for estimating the impact of a treatment on a single unit in panel data settings. The “synthetic control” is a weighted average of control units that balances the treated unit’s pretreatment outcomes and other covariates as closely as possible.
Ben-Michael, Eli   +2 more
openaire   +6 more sources

An Insight into the Medicinal Chemistry Perspective of Macrocyclic Derivatives with Antitumor Activity: A Systematic Review

open access: yesMolecules, 2022
The profound pharmacological properties of macrocyclic compounds have led to their development as drugs. In conformationally pre-organized ring structures, the multiple functions and stereochemical complexity provided by the macrocycle result in high ...
Yan Liang, Ru Fang, Qiu Rao
doaj   +1 more source

Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities

open access: yesViruses, 2023
Antiviral properties of different oxa- and aza-heterocycles are identified and properly correlated with their structural features and discussed in this review article.
Sibasish Manna   +5 more
doaj   +1 more source

Organic Synthetic Methods

open access: yes, 2002
Synthesis is one of the major endeavours of the organic chemist, and the design of a successful synthesis requires a sound knowledge of functional group chemistry, stereochemistry and organic reaction mechanisms. Organic Synthetic Methods introduces the major methods of creating carbon-carbon and carbon-nitrogen bonds, along with functional group ...
James R Hanson   +2 more
openaire   +2 more sources

Prediction Intervals for Synthetic Control Methods [PDF]

open access: yesJournal of the American Statistical Association, 2021
Uncertainty quantification is a fundamental problem in the analysis and interpretation of synthetic control (SC) methods. We develop conditional prediction intervals in the SC framework, and provide conditions under which these intervals offer finite-sample probability guarantees. Our method allows for covariate adjustment and non-stationary data.
Cattaneo, Matias D.   +2 more
openaire   +3 more sources

Synthesis of 5-Fluoroaminobenzothiazoles

open access: yesSynOpen, 2020
A series of 5-fluoro-2-(N-substituted)aminobenzothiazoles were synthesized by intramolecular cyclisation of the corresponding thioureas, which were prepared by treatment of 4-substituted 3-fluoroanilines with appropriate isothiocyanates.
Pooja Sharma   +4 more
doaj   +1 more source

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