Results 11 to 20 of about 1,066,470 (312)
Synthetic Methods of Phosphonopeptides. [PDF]
Phosphonopeptides are phosphorus analogues of peptides and have been widely applied as enzyme inhibitors and antigens to induce catalytic antibodies. Phosphonopeptides generally contain one aminoalkylphosphonic acid residue and include phosphonopeptides with C-terminal aminoalkylphosphonic acids and phosphonopeptides with a phosphonamidate bond.
Xu J.
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Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine. [PDF]
In the context of naturally occurring nitrogen heterocycles, nicotine is a chiral alkaloid present in tobacco plants, which can target and stimulate nicotinic acetylcholine receptors (nAChRs), a class of ligand-gated ion channels commonly located ...
Panda B, Albano G.
europepmc +2 more sources
Synthetic Control Methods for Proportions
Synthetic control methods are extensively utilized in political science for estimating counterfactual outcomes in case studies and difference-in-differences settings, often applied to model counterfactual proportional data. However, the conventional synthetic control methods are designed for univariate outcomes, leading researchers to model ...
Konstantin Bogatyrev, Lukas Stoetzer
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The Inclusive Synthetic Control Method [PDF]
We introduce the inclusive synthetic control method (iSCM), a modification of synthetic control methods that includes units in the donor pool potentially affected, directly or indirectly, by an intervention. This method is ideal for situations where including treated units in the donor pool is essential or where donor units may experience spillover ...
Di Stefano, Roberta, Mellace, Giovanni
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The Augmented Synthetic Control Method [PDF]
The synthetic control method (SCM) is a popular approach for estimating the impact of a treatment on a single unit in panel data settings. The “synthetic control” is a weighted average of control units that balances the treated unit’s pretreatment outcomes and other covariates as closely as possible.
Ben-Michael, Eli +2 more
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The profound pharmacological properties of macrocyclic compounds have led to their development as drugs. In conformationally pre-organized ring structures, the multiple functions and stereochemical complexity provided by the macrocycle result in high ...
Yan Liang, Ru Fang, Qiu Rao
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Antiviral properties of different oxa- and aza-heterocycles are identified and properly correlated with their structural features and discussed in this review article.
Sibasish Manna +5 more
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Synthesis is one of the major endeavours of the organic chemist, and the design of a successful synthesis requires a sound knowledge of functional group chemistry, stereochemistry and organic reaction mechanisms. Organic Synthetic Methods introduces the major methods of creating carbon-carbon and carbon-nitrogen bonds, along with functional group ...
James R Hanson +2 more
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Prediction Intervals for Synthetic Control Methods [PDF]
Uncertainty quantification is a fundamental problem in the analysis and interpretation of synthetic control (SC) methods. We develop conditional prediction intervals in the SC framework, and provide conditions under which these intervals offer finite-sample probability guarantees. Our method allows for covariate adjustment and non-stationary data.
Cattaneo, Matias D. +2 more
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Synthesis of 5-Fluoroaminobenzothiazoles
A series of 5-fluoro-2-(N-substituted)aminobenzothiazoles were synthesized by intramolecular cyclisation of the corresponding thioureas, which were prepared by treatment of 4-substituted 3-fluoroanilines with appropriate isothiocyanates.
Pooja Sharma +4 more
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