Results 61 to 70 of about 213,213 (245)

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, EarlyView.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

The Gold‐Maker of Animal Oil and Prussian Blue Fame — The Chemical and Medicinal Science Philosophy of Johann Conrad Dippel

The Chemical Record, EarlyView.
The radical Pietist Johann Conrad Dippel was a self‐proclaimed adept – a maker of gold and the philosophers’ stone. He was also a magister of theology, a doctor of medicine, and a self‐taught chemist, who coinvented the pigment Prussian Blue together with Johann von Diesbach, became known for his animal pyrolysis oil, his wonder‐wound balm, his ...
Curt Wentrup
wiley   +1 more source

Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility

United European Gastroenterology Journal, EarlyView.
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari, Francesco Calabrese, Andrea Pasta, Greta Lorenzon, Bas Weusten, Jutta Keller, Pierfrancesco Visaggi, Sabine Roman, Elisa Marabotto, Ram Dickman, Jordi Serra, Nicola De Bortoli, Paola Iovino, Daniel Pohl, Dan Dumitrascu, Mentore Ribolsi, Claudia Barber, Serhat Bor, Mark Fox, Rami Sweiss, Vicente Lorenzo‐Zuniga, Filiz Akyuz, Matteo Ghisa, Altay Celebi, Fahmi Shibli, Rainer Dziewas, Ismail Hakkı Kalkan, Jan Tack, Pere Clavé, Silvia Carrion, Ivy Cheng, Noemi Tomsen, Omar Ortega, Sergio Marin Rubio, Nicole Pizzorni, Emilia Michou, Julie Regan, Shaheen Hamdy, Nathalie Rommel, Martina Scharitzer, Olle Ekberg, Antonio Schindler, Renee Speyer, Anna Gillman, Frank Zerbib, Edoardo V. Savarino   +45 more
wiley   +1 more source

PCR detection for syphilis diagnosis: Status and prospects

Journal of clinical laboratory analysis (Print), 2019
Syphilis, a re‐emerging public health problem worldwide caused by Treponema pallidum subsp pallidum (T. pallidum), usually induces systemic and chronic inflammation in hosts who do not receive timely therapy after exposing to high‐risk factors such as ...
Chenglong Zhou, Xiaohong Zhang, Wei Zhang, Junxia Duan, Feijun Zhao   +4 more
semanticscholar   +1 more source

Two Ulcers on the Chin That Developed After Fever: Quiz Case

JEADV Clinical Practice, EarlyView.
Viktor Capiau, Sofie Engelen, An Van Laethem, Francesca Bosisio   +3 more
wiley   +1 more source

Pituitary apoplexy is associated with concurrent or subsequent diagnosis of human immunodeficiency virus

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objective Pituitary apoplexy (PA) is a rare condition caused by hemorrhage or infarction of the pituitary gland with associated risk of cranial neuropathies, endocrinopathies, and even death. Human immunodeficiency virus (HIV) has been shown to have some association with pituitary apoplexy, however, large‐scale studies have not been performed.
Jennifer E. Douglas, Mandy K. Salmon, Rijul S. Kshirsagar, Jacob G. Eide, Caitlin White, Julia Kharlip, Christina Jackson, John Y. K. Lee, Daniel Yoshor, Michael A. Kohanski, James N. Palmer, Nithin D. Adappa   +11 more
wiley   +1 more source

Clinical Manifestations in 32 Cases of Mpox Infection: A Retrospective Study in a Single Dermatology Clinic in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Mpox, a zoonotic orthopox virus, has re‐emerged globally since May 2022. In Tokyo, 168 cases were reported in 2023. About 20% were diagnosed in our department. In this study, we analyzed the clinical and epidemiological characteristics of 32 mpox patients diagnosed in our department in 2023.
Amika Nakazawa, Tomonobu Ito, Takafumi Numata, Noriyasu Sakai, Yukari Okubo, Kazutoshi Harada   +5 more
wiley   +1 more source

National Trends and Reported Risk Factors Among Pregnant Women With Syphilis in the United States, 2012-2016.

Obstetrics and Gynecology, 2019
OBJECTIVE To describe recent syphilis trends among pregnant women and to evaluate the prevalence of reported high-risk behaviors in this population. METHODS We analyzed U.S.
Shivika Trivedi, Charnetta L. Williams, Elizabeth A Torrone, S. Kidd   +3 more
semanticscholar   +1 more source

Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open‐Label Single‐Arm Clinical Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Telogen effluvium (TE) is an acute and diffuse hair loss due to an abnormal increase in telogen hair follicles in response to external or internal factors. Recently, TE attracts global interest as a major cause of hair loss as a sequela of COVID‐19.
Manabu Ohyama, Ryokichi Irisawa, Masaki Uchiyama, Miho Mori, Kazuhiro Aoki, Yuto Ueda, Toru Fujita   +6 more
wiley   +1 more source

Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages

Nature Communications, 2018
Syphilis is a sexually transmitted infection caused by Treponema pallidum subspecies pallidum and may lead to severe complications. Recent years have seen striking increases in syphilis in many countries.
M. Beale, M. Marks, S. Sahi, L. Tantalo, A. Nori, P. French, S. Lukehart, C. Marra, N. Thomson   +8 more
semanticscholar   +1 more source