Results 231 to 240 of about 38,900 (274)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Barriers and facilitators of opioid treatment among Indigenous Syringe Services Program clients. [PDF]

Addict Sci Clin Pract
Stipek J, Mootz JJ, Johnson FL, Hallgren KA, Brown AL, Perron A, Aanji’bide Community Action Board, Alexander C, Greenfield BL.   +8 more
europepmc   +1 more source

Between Exclusion and Legitimacy: Identity Negotiation and Ethical Dilemmas of Chinese Lesbians in the Assisted Reproduction System

Developing World Bioethics, EarlyView.
ABSTRACT In China's current assisted reproduction system, marriage and sexual orientation serve as key entry barriers, leaving lesbians facing institutional exclusion under the dual identities of “unmarried” and “non‐heterosexual.” The marriage system, heterosexual norms, and technical regulations jointly construct the institutional structure that ...
Yuan Liu
wiley   +1 more source

Toward Integrated Models of Infectious Diseases, Harm Reduction, and Primary Care. [PDF]

Open Forum Infect Dis
Mitragotri S, Reddy A, Shah K, Zhu DT.
europepmc   +1 more source

Repeated injection of pooled frozen allogeneic umbilical cord blood mesenchymal stromal cells in 5 flat‐racing horses

Equine Veterinary Education, EarlyView.
Summary Background Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.
A. Merchan Muñoz, N. Coté, T. Koch, S. Mehrpouyan, A. H. Alizadeh, K. A. Russell, G. Monteith, J. Koenig   +7 more
wiley   +1 more source

Evaluating the implementation and impact of harm reduction vending machines in veterans supportive housing settings: a mixed-methods study protocol. [PDF]

Harm Reduct J
Rife-Pennington T, Douglas MP, Apana NK, Sinha S, Pennington DL.   +4 more
europepmc   +1 more source

Aural plaques: Considerations on autohaemotherapy treatment in four Mangalarga Marchador crossbred horses

Equine Veterinary Education, EarlyView.
Summary The occurrence of Aural Plaques (AP) in horses, attributed to infection with Equus caballus Papillomavirus (EcPV), has become increasingly prevalent in equine breeding populations. Major challenges in managing this condition include genetic susceptibility to the virus, significant variability in individual immune responses among horses and the ...
E. Bastianetto, M. I. de Azevedo, I. S. Ferrão, P. Fantini, E. M. M. Lima, M. B. Castro, C. B. de Melo   +6 more
wiley   +1 more source

Global survey on the utilisation and experiences with different retrobulbar anaesthesia techniques in horses

Equine Veterinary Journal, EarlyView.
Abstract Background Retrobulbar anaesthesia (RBA) is relevant for ocular surgery in standing sedated horses. Objectives Gathering insights on experiences with RBA techniques. Study Design Cross‐sectional survey. Methods An online survey collected information on the respondents' professional background, indications, injection methods, use of ultrasound ...
Simona Lieberth, Katharina Thieme, Christian Dancker, Roswitha Merle, Johanna Corinna Eule   +4 more
wiley   +1 more source

Tribally-affiliated syringe services programs in the United States: a brief report. [PDF]

Harm Reduct J
Allen ST, Keane E, Alexander C, Day S, Kebec P, Medley A, Johnson F, Hughes P, Barney B, Walls M.   +9 more
europepmc   +1 more source