Results 71 to 80 of about 38,900 (274)

Is PEPFAR Funding for Key Populations Aligned with the Epidemiologic Burden? [PDF]

open access: yes, 2016
Key populations (KPs)—gay, bisexual, and other men who have sex with men (MSM); people who inject drugs (PWID), female sex workers (FSW); and transgender people (TG)—are at significantly higher risk for HIV, face a higher burden of disease, have less ...

core  

Frequency, factors and costs associated with injection site infections: findings from a national multi-site survey of injecting drug users in England. [PDF]

open access: yes, 2008
BACKGROUND: Injection site infections among injecting drug users (IDUs) have been associated with serious morbidity and health service costs in North America.
Hickman, Matthew   +4 more
core   +3 more sources

Implementation Gaps in US Syringe Services Programs, 2022

open access: yesJAMA Network Open
This cross-sectional study examines implementation gaps in syringe service programs by US Census division, urbanicity, and level of need.
Humphrey, Jamie L.   +9 more
openaire   +1 more source

Access to Syringe Services Programs — Kentucky, North Carolina, and West Virginia, 2013–2017 [PDF]

open access: yesMMWR. Morbidity and Mortality Weekly Report, 2018
The Appalachian region of the United States is experiencing a large increase in hepatitis C virus (HCV) infections related to injection drug use (IDU) (1). Syringe services programs (SSPs) providing sufficient access to safe injection equipment can reduce hepatitis C transmission by 56%; combined SSPs and medication-assisted treatment can reduce ...
Bixler, Danae   +10 more
openaire   +2 more sources

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid   +6 more
wiley   +1 more source

Responding to a surge in overdose deaths: perspectives from US syringe services programs

open access: yesHarm Reduction Journal, 2022
Abstract Background US overdose deaths have reached a record high. Syringe services programs (SSPs) play a critical role in addressing this crisis by providing multiple services to people who use drugs (PWUD) that help prevent overdose death.
Madeline C. Frost   +15 more
openaire   +3 more sources

Mimicking Block Copolymer Self‐Assembly with One‐Pot Synthesized Polyphosphoester Gradient Copolymers

open access: yesAdvanced Functional Materials, EarlyView.
Degradable Polyphosphoester (PPE) gradient copolymers (GCPs) are synthesized via one‐pot copolymerization. We show that GCPs self‐assemble into nanostructures like polymersomes, effectively mimicking the behavior of traditional BCPs. The gradient strength is key, with softer gradients favoring micelles.
Suna Azhdari   +7 more
wiley   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Improving HIV service delivery for people who inject drugs in Kazakhstan: study protocol for the Bridge stepped-wedge trial

open access: yesImplementation Science, 2019
Background People who inject drugs (PWID) in Kazakhstan face many barriers to HIV testing as well as to accessing HIV care, to retention in HIV care, and to initiating and adhering to anti-retroviral treatment (ART).
Tara McCrimmon   +14 more
doaj   +1 more source

Syringe service program-based telemedicine linkage to opioid use disorder treatment: protocol for the STAMINA randomized control trial

open access: yesBMC Public Health, 2021
Background A key strategy for mitigating the current opioid epidemic is expanded access to medications for treating opioid use disorder (MOUD). However, interventions developed to expand MOUD access have limited ability to engage opioid users at higher ...
Dennis P. Watson   +8 more
doaj   +1 more source

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