Results 141 to 150 of about 633,595 (269)

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Making the Case for Syringe Services Programs [PDF]

Public Health Reports®, 2020
openaire   +2 more sources

Design and Characterization of DX‐Tile DNA Nanostar‐Based Hydrogels

Advanced Science, EarlyView.
In this study, the authors demonstrated that DNA DX‐tile‐based multi‐arm motifs can be used to assemble pure DNA hydrogels, offering greater design flexibility and enhanced control over their mechanical properties and functionalization capabilities compared to single duplex‐based DNA hydrogels.
Dylan V. Scarton, Alessandra B. Coogan, Peter M. Touma, Eray O. Tulun, Katie A. Harrison, Jack Buchen, Richard C. Steiner, Christopher R. Fellin, Hunter G. Mason, Chih‐Hsiang Hu, Sally Farag, Xiaoning Yuan, Shailly Jariwala, Remi Veneziano   +13 more
wiley   +1 more source

Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal [PDF]

, 2018
This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with
Clark, Peter, Cooney, Kevin, DiMeglio, M., Dubensky, J., Gulati, S., Lathrop, S., Lee, Marvin J. H., Minupuri, A., Nguyen, Olivia, Patel, P., Schadt, Sam A., Umapathy, S., Zheng, S.   +12 more
core  

Funding and Delivery of Syringe Services Programs in the United States, 2022

American Journal of Public Health
Objectives. To describe the current financial health of syringe services programs (SSPs) in the United States and to assess the predictors of SSP budget levels and associations with delivery of public health interventions. Methods. We surveyed all known SSPs operating in the United States from February to June 2022 (n = 456), of which 68% responded ...
Shelley N. Facente, Jamie L. Humphrey, Christopher Akiba, Sheila V. Patel, Lynn D. Wenger, Hansel Tookes, Ricky N. Bluthenthal, Paul LaKosky, Stephanie Prohaska, Terry Morris, Alex H. Kral, Barrot H. Lambdin   +11 more
openaire   +4 more sources

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

The Public Health Impact of Needle Exchange Programs in the United States and Abroad: Summary, Conclusions, and Recommendations [PDF]

, 1993
The goal of the project was: "To assess the public health impact of needle exchange programs." Fourteen research questions were identified; Chapters 5 through 18 of Volume I of the report each address one of these research questions.
Arthur L. Reingold, Peter Lurie
core  

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Improving access to HIV care among people who inject drugs through tele-harm reduction: a qualitative analysis of perceived discrimination and stigma

Harm Reduction Journal
Background Tele-harm reduction (THR) is a telehealth-enhanced, peer-led, harm reduction intervention delivered within a trusted syringe services program (SSP) venue.
Carolina Scaramutti, Belén Hervera, Yanexy Rivera, Teresa A. Chueng, David W. Forrest, Edward Suarez, David P. Serota,, Hatoun Alkamli, Katrina Ciraldo, Tyler S. Bartholomew, Hansel E. Tookes   +10 more
doaj   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source