Results 221 to 230 of about 633,595 (269)

Charge Directed Selective Co‐Assembly of Ionic Complementary Peptide Binary Mixtures

Small, EarlyView.
Multi‐component peptide systems enable the development of multi‐functional and tunable materials, yet, controlling the co‐assembly of such complex systems remains challenging. This study demonstrates that rational design of peptide charge distribution, together with controlling parameters (pH, stoichiometry, and concentration), can guide selective co ...
Abdulwahhab Khedr, Mohamed A. N. Soliman, Alfred Corrigan, Tarsem Sahota, Rachel Armitage, Natalie Allcock, Jeyapriya T. Jegadeesan, Mahetab H. Amer, Reem Alazragi, Zeeshan Ahmad, Jacek K. Wychowaniec, Mohamed A. Elsawy   +11 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Effect of ‘combing’ on intramuscular sedation in pigs in a clinical setting—A randomised trial

Veterinary Record, EarlyView.
Abstract Background Pigs pose distinct challenges to the anaesthetist due to their temperament, the limitations of manual restraint and species‐specific anatomical features. Despite the importance of minimising stress during clinical procedures, gentle handling techniques tailored for pigs in a clinical setting have yet to be clearly described or ...
Kaitlynn C. Ban, Carolina H. Ricco Pereira, Kirk A. Muñoz, Chiara E. Hampton, Gianluca Bini, Phillip Lerche   +5 more
wiley   +1 more source

Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil

Veterinary Record, EarlyView.
Abstract Background Leptospirosis is a significant zoonosis in tropical regions, where poor sanitation and favourable climate aid its spread. Synanthropic animals such as the cane toad (Rhinella jimi), which share environments with both people and wild and domestic animals, may harbour Leptospira and contribute to urban and rural transmission cycles ...
Karla N. de Souza Rocha, Aline de Lima Peixoto, Lucila S. de Medeiros Pereira, Debora Ferreira Cardoso, Maria L. C. Rodrigues Silva, Sérgio S. de Azevedo, Juliana P. F. de Oliveira, Clebert J. Alves, Mozar Alves Fonseca, Severino S. dos Santos Higino   +9 more
wiley   +1 more source

Toronto's drug policy paradox: Harm reduction sites and drug police occurrences in Toronto neighborhoods (1992–2020)

Criminology, EarlyView.
Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, EarlyView.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source

A cost–benefit analysis of the implementation and scale‐up of harm reduction interventions in the Australian Capital Territory

Addiction, EarlyView.
Abstract Background and aims Harm reduction interventions aim to reduce negative consequences of drug use. We aimed to estimate the cost, health impact and economic benefits of current, expanded and new harm reduction interventions for people who use drugs in the Australian Capital Territory.
Anna L. Bowring, Tom Tidhar, Anna Olsen, Christopher Bailie, Kelvin Burke, Rowan Martin‐Hughes, Helen Keane, Paul Dietze, Nick Scott   +8 more
wiley   +1 more source

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, EarlyView.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source