Results 91 to 100 of about 303,922 (266)

Scalable System-on-Chip Design

open access: yes, 2017
The crisis of technology scaling led the industry of semiconductors towards the adoption of disruptive technologies and innovations to sustain the evolution of microprocessors and keep under control the timing of the design cycle. Multi-core and many-core architectures sought more energy-efficient computation by replacing a power-hungry processor with ...
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Exploring cyclic olefin copolymer (COC) for flexible silver nanowire electrode

open access: yesScientific Reports
The development of flexible electronic devices has been a primary focus in various fields, and silver nanowire (Ag NW) networks show significant promise due to their unique electrical and mechanical properties.
Fadi Dawaymeh   +3 more
doaj   +1 more source

Strong field enhancement and ultra-narrow linewidth based on the coupling of anapole/gap modes in silicon nanodimer-ring arrays

open access: yesResults in Physics
All-dielectric metamaterials have recently received significant attention in the field of nanophotonics, due to their negligible dissipative losses and strong polariton response compared with metallic metamaterials.
Xiongwu Ju   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

SymPET, a waveform digitizing "System on Chip" for ultra-high resolution TOF PET: design concept and preliminary studies. [PDF]

open access: yesIEEE Nucl Sci Symp Conf Rec (1997), 2022
Flood K   +9 more
europepmc   +1 more source

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