Results 101 to 110 of about 328,138 (300)

Neuromorphic Computing with Memcapacitors: Advancements, Challenges, and Future Directions

Advanced Electronic Materials
Modern applications demand immense data processing and computational power, yet conventional architectures, constrained by the Von Neumann bottleneck and data presentation, struggle to meet these requirements.
Nada AbuHamra, Muhammad Umair Khan, Eman Hassan, Mahmoud Al Qutayri, Baker Mohammad   +4 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

An Intelligent Auxiliary Vacuum Brake System [PDF]

, 2009
The purpose of this paper focuses on designing an intelligent, compact, reliable, and robust auxiliary vacuum brake system (VBS) with Kalman filter and self-diagnosis scheme.
Li, Jiun-Yi, Li, Shih-Fan, Lin, Jhih-Yu, Tong, Chia-Chang   +3 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A formal semantics for control and data flow in the gannet service-based system-on-chip architecture [PDF]

, 2008
There is a growing demand for solutions which allow the design of large and complex reconfigurable Systems-on- Chip (SoC) at high abstraction levels. The Gannet project proposes a functional programming approach for high-abstraction design of very large
Vanderbauwhede, W.
core   +1 more source

Runtime Scheduling, Allocation, and Execution of Real-Time Hardware Tasks onto Xilinx FPGAs Subject to Fault Occurrence

International Journal of Reconfigurable Computing, 2013
This paper describes a novel way to exploit the computation capabilities delivered by modern Field-Programmable Gate Arrays (FPGAs), not only towards a higher performance, but also towards an improved reliability. Computation-specific pieces of circuitry
Xabier Iturbe, Khaled Benkrid, Chuan Hong, Ali Ebrahim, Tughrul Arslan, Imanol Martinez   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

System-on-chip Computing and Interconnection Architectures for Telecommunications and Signal Processing [PDF]

This dissertation proposes novel architectures and design techniques targeting SoC building blocks for telecommunications and signal processing applications.
L'INSALATA, NICOLA EUGENIO
core  

Instruction-Level Abstraction (ILA): A Uniform Specification for System-on-Chip (SoC) Verification

, 2018
Modern Systems-on-Chip (SoC) designs are increasingly heterogeneous and contain specialized semi-programmable accelerators in addition to programmable processors.
Gupta, Aarti, Huang, Bo-Yuan, Malik, Sharad, Subramanyan, Pramod, Vizel, Yakir, Zhang, Hongce   +5 more
core   +1 more source