Results 141 to 150 of about 40,752,794 (367)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Why Do Life Insurance Policyholders Lapse? The Roles of Income, Health and Bequest Motive Shocks [PDF]
Previous research has shown that the reasons for lapsation have important implications regarding the effects of the emerging life settlement market on consumer welfare.
Edward Kung, Hanming Fang
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Does Economic Uncertainty Affect the Decision to Bear Children? Evidence from East and West Germany [PDF]
During their social, political and economic transition, the countries of Central and Eastern Europe experienced significant economic uncertainty. Many of these countries also experienced sharply falling fertility rates.
Jeffrey B. Nugent, Sumon Kumar Bhaumik
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An adaptive high-gain observer for nonlinear systems
, 2010 Nicolas Boizot +2 more
openalex +2 more sources
Ten principles relevant to health research among Indigenous Australian populations [PDF]
As committed Indigenous health researchers in Australia, these researchers aim to provide the answers to key questions relating to health that might enable Indigenous Australians to live the lives that they would choose to live. Working with Indigenous
Lisa M. Jamieson
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Deep Learning-Based Real-Time Weapon Detection System [PDF]
, 2023 Amjed Al‐Mousa +2 more
openalex +1 more source
Computing Dynamic Heterogeneous-Agent Economies: Tracking the Distribution [PDF]
Theoretical formulations of dynamic heterogeneous-agent economiestypically include a distribution as an aggregate state variable. This paperintroduces a method for computing equilibrium of these models by including a distribution directly as a state ...
Grey Gordon
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