Results 61 to 70 of about 5,197,383 (319)
Pharmacogenomics: a systems approach [PDF]
WIREs Systems Biology and Medicine, 2010 AbstractPharmacogenetics and pharmacogenomics involve the study of the role of inheritance in individual variation in drug response, a phenotype that varies from potentially life‐threatening adverse drug reactions to equally serious lack of therapeutic efficacy.
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Programming a Distributed Application The TUXEDO
, 2007 This paper describes the rich set of communication techniques available to TUXEDO System programmers for writing distributed applications. The TUXEDO System supports four distinct communication methods that are versatile and easy to use yet powerful ...
System Approach
core
System Safety Bookshelf: System Safety for the 21st Century, 2nd Edition
, 2023 Over many decades System Safety has evolved from a more re-active nature - learning from failures and improving – not really suitable for high consequence enterprises - to today’s more pro-active form.
Jones, Malcolm
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MOTIVATION COMPONENT COMMUNICATIVE SKILLS DEVELOPMENT IN THE CONTEXT OF ADAPTATION PERIOD IN CRIMEA [PDF]
Krymskij Naučnyj Vestnik, 2015 The concept of «system approach» to learning, which considers all the components in close relationship with each other is considered. One of the urgent problems of modern pedagogy — developing communicative abilities on the basis of system approach is ...
Antonina Drozdova
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Polynomial approach to control system design for a magnetic levitation system
, 2015 The contribution deals with the problem of designing a control system for a magnetic levitation apparatus. The proposed procedure uses a polynomial approach for control system design with control structure having two feedback controllers.
Gazdoš, František +3 more
core
A Statistical Approach for Distribution System State Estimation
Power system state estimation is a useful technique that enables the system to be monitored when sufficient measurements are not available. Although it has been practiced for a long time, distribution system state estimation (DSSE) is still challenging ...
Ibrahim Gursu Tekdemir
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source