National Essential Diagnostics List development as an opportunity to expand frontline diagnostic testing at barangay health stations in the Philippines. [PDF]
Kanamori S +11 more
europepmc +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Diagnostic completeness: the missing link in antimicrobial stewardship in low- and middle-income countries. [PDF]
Pan Q, Chen X.
europepmc +1 more source
State of Ohio : strategic plan
Title from URL of PDF document (viewed Nov. 1, 2005).; "6/20/2005"--P. 1, etc.; Harvested from the web on 11/1/055.3.1.00 general ledger (135 p.) -- 5.3.2.00 accounts payable (77 p.) -- 5.3.3.00 procurement (180 p.) -- 5.3.4.00 grants, project costing ...
Ohio Administrative Knowledge System.
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Biomechanical Vitreous Alterations Detected by Strain Elastography Beyond Conventional B-Mode Ultrasound in Psoriatic Disease. [PDF]
Mendonça JA, Dos Santos MAS, Gambero A.
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Health systems readiness for integration of point-of-care digital diagnostic tools for acute febrile illness in Ghana: a mixed-methods study protocol. [PDF]
Dele-Olowu SM +7 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source

