Results 181 to 190 of about 28,979,637 (350)

Analysing the uncertain future of copper with three exploratory system dynamics models

, 2012
High copper prices, the prospect of a transition to a more sustainable energy mix and increasing copper demands from emerging economies have not led to an in-creased attention to the base metal copper in mineral scarcity discussions. The copper system is
Kwakkel, J.H. (author), Auping, W., Auping, W. (author), Pruyt, E. (author), Kwakkel, J.H., Pruyt, E.   +5 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Correction: Tracing the threads: a system dynamics and network diffusion model of kangaroo care implementation in neonatal care. [PDF]

Implement Sci Commun
Nyantakyi E, Block P, Clack L, Schultes MT.   +3 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Tracing the threads: a system dynamics and network diffusion model of kangaroo care implementation in neonatal care. [PDF]

Implement Sci Commun
Nyantakyi E, Block P, Clack L, Schultes MT.   +3 more
europepmc   +1 more source

Strategies in an uncertain world: A Systems Dynamics analysis of different flood protection strategies

, 2016
Flood defences are a key issue in low lying coastal areas. These defences can protect the economy of hinterland regions along with countless lives. A onceptually simple abstraction of the complexity of a flood defence system is formulated in system ...
Meeuwsen, Sjoerd (author), Slinger, J (author), Klein, Raphael (author)   +2 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

System dynamics at sixty: the path forward

, 2018
J. Sterman
semanticscholar   +1 more source

Research on the intervention mechanism and dynamic evolution of the digital divide's impact on the physical and mental health of older adults: a system dynamics perspective. [PDF]

Front Public Health
Shao T, Chen Y, Ren B, Gang S.
europepmc   +1 more source

Exploration of the Growing Trend of Electric Vehicles in Beijing with System Dynamics method and Vensim model

, 2014
This research is conducted to explore the growing trend of private vehicles in Beijing, China, in the coming 25 years using the system dynamics (SD) method. The vensim software is used to build the SD model and do simulations. First, the paper introduces
Zhang, C., Zhang, C. (author), Qin, C. (author), Qin, C.   +3 more
core